Generation of human iPSCs from human prostate cancer-associated
fibroblasts IBPi002-A

J 2018

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

KAHOUNOVÁ, Zuzana, Eva SLABÁKOVÁ, Lucia BINÓ, Ján REMŠÍK, Radek FEDR et. al.

Basic information

Original name

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

Authors

KAHOUNOVÁ, Zuzana (203 Czech Republic), Eva SLABÁKOVÁ (203 Czech Republic), Lucia BINÓ (703 Slovakia), Ján REMŠÍK (703 Slovakia), Radek FEDR (203 Czech Republic), Jan BOUCHAL (203 Czech Republic), Daniela KURFŰRSTOVÁ (203 Czech Republic), Radek VRTĚL (203 Czech Republic), Vladimír ŠTUDENT (203 Czech Republic), Lucie JUREČKOVÁ (203 Czech Republic), Volodymyr POROKH (804 Ukraine, belonging to the institution), Aleš HAMPL (203 Czech Republic, belonging to the institution) and Karel SOUČEK (203 Czech Republic, guarantor)

Edition

Stem Cell Research, Amsterdam, ELSEVIER SCIENCE, 2018, 1873-5061

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10601 Cell biology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.929

RIV identification code

RIV/00216224:14110/18:00101364

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.scr.2018.11.006

UT WoS

000452639700039

Keywords in English

prostate cancer

Abstract

V originále

A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5 (TM) Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.

Links

GA15-11707S, research and development project

Name: Centrosomální abnormality u lidských pluripotentních kmenových buněk.

Investor: Czech Science Foundation

LM2015062, research and development project

Name: Národní infrastruktura pro biologické a medicínské zobrazování

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/C/1418/2017, interní kód MU

Name: Extracelulární faktory ovlivňující metabolismus centrozomů v lidských pluripotentních kmenových buňkách

Investor: Masaryk University, Rector's Program

Citovat

KAHOUNOVÁ, Zuzana, Eva SLABÁKOVÁ, Lucia BINÓ, Ján REMŠÍK, Radek FEDR, Jan BOUCHAL, Daniela KURFŰRSTOVÁ, Radek VRTĚL, Vladimír ŠTUDENT, Lucie JUREČKOVÁ, Volodymyr POROKH, Aleš HAMPL and Karel SOUČEK. Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A. Stem Cell Research. Amsterdam: ELSEVIER SCIENCE, 2018, vol. 33, DEC 2018, p. 255-259. ISSN 1873-5061. Available from: https://dx.doi.org/10.1016/j.scr.2018.11.006.

@article{1470472,
   author = {Kahounová, Zuzana and Slabáková, Eva and Binó, Lucia and Remšík, Ján and Fedr, Radek and Bouchal, Jan and Kurfűrstová, Daniela and Vrtěl, Radek and Študent, Vladimír and Jurečková, Lucie and Porokh, Volodymyr and Hampl, Aleš and Souček, Karel},
   article_location = {Amsterdam},
   article_number = {DEC 2018},
   doi = {http://dx.doi.org/10.1016/j.scr.2018.11.006},
   keywords = {prostate cancer},
   language = {eng},
   issn = {1873-5061},
   journal = {Stem Cell Research},
   title = {Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A},
   url = {https://www.sciencedirect.com/science/article/pii/S1873506118302757?via%3Dihub},
   volume = {33},
   year = {2018}
}

TY  - JOUR
ID  - 1470472
AU  - Kahounová, Zuzana - Slabáková, Eva - Binó, Lucia - Remšík, Ján - Fedr, Radek - Bouchal, Jan - Kurfűrstová, Daniela - Vrtěl, Radek - Študent, Vladimír - Jurečková, Lucie - Porokh, Volodymyr - Hampl, Aleš - Souček, Karel
PY  - 2018
TI  - Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A
JF  - Stem Cell Research
VL  - 33
IS  - DEC 2018
SP  - 255-259
EP  - 255-259
PB  - ELSEVIER SCIENCE
SN  - 18735061
KW  - prostate cancer
UR  - https://www.sciencedirect.com/science/article/pii/S1873506118302757?via%3Dihub
N2  - A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5 (TM) Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.
ER  -

KAHOUNOVÁ, Zuzana, Eva SLABÁKOVÁ, Lucia BINÓ, Ján REMŠÍK, Radek FEDR, Jan BOUCHAL, Daniela KURF$\backslash$H URSTOVÁ, Radek VRTĚL, Vladimír ŠTUDENT, Lucie JUREČKOVÁ, Volodymyr POROKH, Aleš HAMPL and Karel SOUČEK. Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A. \textit{Stem Cell Research}. Amsterdam: ELSEVIER SCIENCE, 2018, vol.~33, DEC 2018, p.~255-259. ISSN~1873-5061. Available from: https://dx.doi.org/10.1016/j.scr.2018.11.006.

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