Stable, nanometer-thick oxygen-containing plasma polymer films
suited for enhanced biosensing

J 2018

Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing

HEGEMANN, Dirk, Ivan INDUTNYI, Lenka ZAJÍČKOVÁ, Ekaterina MAKHNEVA, Zdeněk FARKA et. al.

Basic information

Original name

Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing

Authors

HEGEMANN, Dirk (756 Switzerland, guarantor), Ivan INDUTNYI (804 Ukraine), Lenka ZAJÍČKOVÁ (203 Czech Republic, belonging to the institution), Ekaterina MAKHNEVA (643 Russian Federation, belonging to the institution), Zdeněk FARKA (203 Czech Republic, belonging to the institution), Yuriy USHENIN (804 Ukraine) and Marianne VANDENBOSSCHE (756 Switzerland)

Edition

Plasma Processes and Polymers, Weinheim, Wiley-VCH, 2018, 1612-8850

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.173

RIV identification code

RIV/00216224:14740/18:00104600

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1002/ppap.201800090

UT WoS

000450356700002

Keywords in English

functionality; immunosensing; nano-layers; plasma coating; surface plasmon resonance

Abstract

V originále

Stable surface functionalization is required in many applications such as in biosensing. For this purpose, hydrocarbon-based plasma polymer films (PPFs) were investigated by controlling cross-linking and film structure at the nanoscale, while functional groups were incorporated using a CO2/C2H4 low pressure plasma. In particular, an oxygen-rich termination layer of 1 nm (top layer) was gradually deposited onto a more cross-linked PPF (base layer) with varying thickness (<20 nm) yielding highly stable yet functional a-C:H:O films as compared to conventional oxygen-rich PPFs. Such stabilized nano-layers provided a homogeneous functionalization of Au-coated (flat) biochips as used for immunosensing as well as of nanostructured Au-coated surfaces explored for enhanced biosensing. The used periodic grating coated by the highly stable a-C:H:O nano-layer can be adjusted to the required environmental refractive index range yielding a distinct sensitivity enhancement for biosensing.

Links

LM2015043, research and development project

Name: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)

Investor: Ministry of Education, Youth and Sports of the CR

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

HEGEMANN, Dirk, Ivan INDUTNYI, Lenka ZAJÍČKOVÁ, Ekaterina MAKHNEVA, Zdeněk FARKA, Yuriy USHENIN and Marianne VANDENBOSSCHE. Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing. Plasma Processes and Polymers. Weinheim: Wiley-VCH, 2018, vol. 15, No 11, p. 1-9. ISSN 1612-8850. Available from: https://dx.doi.org/10.1002/ppap.201800090.

@article{1471510,
   author = {Hegemann, Dirk and Indutnyi, Ivan and Zajíčková, Lenka and Makhneva, Ekaterina and Farka, Zdeněk and Ushenin, Yuriy and Vandenbossche, Marianne},
   article_location = {Weinheim},
   article_number = {11},
   doi = {http://dx.doi.org/10.1002/ppap.201800090},
   keywords = {functionality; immunosensing; nano-layers; plasma coating; surface plasmon resonance},
   language = {eng},
   issn = {1612-8850},
   journal = {Plasma Processes and Polymers},
   title = {Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing},
   url = {https://onlinelibrary.wiley.com/doi/full/10.1002/ppap.201800090},
   volume = {15},
   year = {2018}
}

TY  - JOUR
ID  - 1471510
AU  - Hegemann, Dirk - Indutnyi, Ivan - Zajíčková, Lenka - Makhneva, Ekaterina - Farka, Zdeněk - Ushenin, Yuriy - Vandenbossche, Marianne
PY  - 2018
TI  - Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing
JF  - Plasma Processes and Polymers
VL  - 15
IS  - 11
SP  - 1-9
EP  - 1-9
PB  - Wiley-VCH
SN  - 16128850
KW  - functionality
KW  - immunosensing
KW  - nano-layers
KW  - plasma coating
KW  - surface plasmon resonance
UR  - https://onlinelibrary.wiley.com/doi/full/10.1002/ppap.201800090
N2  - Stable surface functionalization is required in many applications such as in biosensing. For this purpose, hydrocarbon-based plasma polymer films (PPFs) were investigated by controlling cross-linking and film structure at the nanoscale, while functional groups were incorporated using a CO2/C2H4 low pressure plasma. In particular, an oxygen-rich termination layer of 1 nm (top layer) was gradually deposited onto a more cross-linked PPF (base layer) with varying thickness (<20 nm) yielding highly stable yet functional a-C:H:O films as compared to conventional oxygen-rich PPFs. Such stabilized nano-layers provided a homogeneous functionalization of Au-coated (flat) biochips as used for immunosensing as well as of nanostructured Au-coated surfaces explored for enhanced biosensing. The used periodic grating coated by the highly stable a-C:H:O nano-layer can be adjusted to the required environmental refractive index range yielding a distinct sensitivity enhancement for biosensing.
ER  -

HEGEMANN, Dirk, Ivan INDUTNYI, Lenka ZAJÍČKOVÁ, Ekaterina MAKHNEVA, Zdeněk FARKA, Yuriy USHENIN and Marianne VANDENBOSSCHE. Stable, nanometer-thick oxygen-containing plasma polymer films suited for enhanced biosensing. \textit{Plasma Processes and Polymers}. Weinheim: Wiley-VCH, 2018, vol.~15, No~11, p.~1-9. ISSN~1612-8850. Available from: https://dx.doi.org/10.1002/ppap.201800090.

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