Detailed Information on Publication Record
2018
CAPILLARY ELECTROPHORETIC ANALYSIS OF EXHALED BREATH CONDENSATE IN THE DIAGNOSIS OF GASTROESOPHAGEAL REFLUX DISEASE
KUBÁŇ, Petr, Pavol ĎURČ, Júlia LAČNÁ, Michal GREGUŠ, František FORET et. al.Basic information
Original name
CAPILLARY ELECTROPHORETIC ANALYSIS OF EXHALED BREATH CONDENSATE IN THE DIAGNOSIS OF GASTROESOPHAGEAL REFLUX DISEASE
Authors
KUBÁŇ, Petr (203 Czech Republic, guarantor, belonging to the institution), Pavol ĎURČ (703 Slovakia, belonging to the institution), Júlia LAČNÁ (703 Slovakia, belonging to the institution), Michal GREGUŠ (703 Slovakia, belonging to the institution), František FORET (203 Czech Republic, belonging to the institution), Jiří DOLINA (203 Czech Republic, belonging to the institution), Štefan KONEČNÝ (703 Slovakia, belonging to the institution), Martina DOUBKOVÁ (203 Czech Republic, belonging to the institution), Dagmar KINDLOVÁ (203 Czech Republic, belonging to the institution), Eva POKOJOVÁ (203 Czech Republic, belonging to the institution) and Jana SKŘIČKOVÁ (203 Czech Republic, belonging to the institution)
Edition
HUNGARIAN JOURNAL OF INDUSTRY AND CHEMISTRY, WARSAW, DE GRUYTER POLAND SP ZOO, 2018, 0133-0276
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10406 Analytical chemistry
Country of publisher
Poland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 0.084 in 2002
RIV identification code
RIV/00216224:14740/18:00106949
Organization unit
Central European Institute of Technology
UT WoS
000440079700006
Keywords in English
capillary electrophoresis; exhaled breath condensate; ionic analysis; diagnosis; gastroesophageal reflux disease
Tags
International impact, Reviewed
Změněno: 4/3/2019 12:28, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
In this work, capillary electrophoresis with contactless conductometric detection (CCD) was used for the analysis of the ionic content of exhaled breath condensate (EBC) to differentiate between healthy individuals and patients with gastroesophageal reflux disease (GERD). The exhaled breath condensate was collected using a miniature sample collection device and the content analyzed using a separation electrolyte composed of 20 mM 2-(N-morpholino)ethanesulfonic acid, 20 mM L-histidine, 2 mM 18-Crown-6 and 30 mu M cetyltrimethylammonium bromide. The separation of anions took less than 2.5 minutes, while the cations were separated in less than 1.5 minutes. The most significantly elevated ions in the group of patients suffering from gastroesophageal reflux disease were chloride, nitrate, propionate and butyrate. Although the number of subjects was too small to draw definite conclusions with regard to the discriminatory power of these ions, the pilot data are promising for EBC as a useful non-invasive alternative for other methods used in the diagnosis of gastroesophageal reflux disease.
Links
| NV17-31945A, research and development project |
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