DROBISZ, Dominik and Alena DAMBORSKÁ. Deep brain stimulation targets for treating depression. BEHAVIOURAL BRAIN RESEARCH. Amsterdam: Elsevier Science, 2019, vol. 359, Feb 2019, p. 266-273. ISSN 0166-4328. Available from: https://dx.doi.org/10.1016/j.bbr.2018.11.004.
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Basic information
Original name Deep brain stimulation targets for treating depression
Authors DROBISZ, Dominik (203 Czech Republic, belonging to the institution) and Alena DAMBORSKÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition BEHAVIOURAL BRAIN RESEARCH, Amsterdam, Elsevier Science, 2019, 0166-4328.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.977
RIV identification code RIV/00216224:14110/19:00108940
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.bbr.2018.11.004
UT WoS 000456222600032
Keywords in English Deep brain stimulation; Major depressive disorder; Treatment-resistant depression
Tags 14110222, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 26/2/2020 15:24.
Abstract
Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD in the subgenual anterior cingulate cortex, the ventral capsule/ventral striatum, the nucleus accumbens, the lateral habenula, the inferior thalamic peduncle, the medial forebrain bundle, and the bed nucleus of the stria terminalis. Optimal stimulation targets, however, have not yet been determined. Here we provide updated knowledge substantiating the suitability of each of the current and potential future DBS targets for treating depression. In this review, we discuss the future outlook for DBS treatment of depression in light of the fact that antidepressant effects of DBS can be achieved using different targets.
Links
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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