J 2019

Deep brain stimulation targets for treating depression

DROBISZ, Dominik and Alena DAMBORSKÁ

Basic information

Original name

Deep brain stimulation targets for treating depression

Authors

DROBISZ, Dominik (203 Czech Republic, belonging to the institution) and Alena DAMBORSKÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

BEHAVIOURAL BRAIN RESEARCH, Amsterdam, Elsevier Science, 2019, 0166-4328

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.977

RIV identification code

RIV/00216224:14110/19:00108940

Organization unit

Faculty of Medicine

DOI

UT WoS

000456222600032

Keywords in English

Deep brain stimulation; Major depressive disorder; Treatment-resistant depression

Tags

Tags

International impact, Reviewed
Změněno: 26/2/2020 15:24, Mgr. Pavla Foltynová, Ph.D.

Abstract

V originále

Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD in the subgenual anterior cingulate cortex, the ventral capsule/ventral striatum, the nucleus accumbens, the lateral habenula, the inferior thalamic peduncle, the medial forebrain bundle, and the bed nucleus of the stria terminalis. Optimal stimulation targets, however, have not yet been determined. Here we provide updated knowledge substantiating the suitability of each of the current and potential future DBS targets for treating depression. In this review, we discuss the future outlook for DBS treatment of depression in light of the fact that antidepressant effects of DBS can be achieved using different targets.

Links

LQ1601, research and development project
Name: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR