HANÁKOVÁ, Kateřina, David POTĚŠIL, Ondřej BERNATÍK, Igor ČERVENKA, Matěj RÁDSETOULAL, Vítězslav BRYJA and Zbyněk ZDRÁHAL. SEMIQUANTITATIVE ASSESSMENT OF DISHEVELLED-3 PHOSPHORYLATION STATUS BY MASS SPECTROMETRY. HUNGARIAN JOURNAL OF INDUSTRY AND CHEMISTRY. 2018, vol. 46, No 1, p. 3-6. ISSN 0133-0276. Available from: https://dx.doi.org/10.1515/hjic-2018-0002.
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Basic information
Original name SEMIQUANTITATIVE ASSESSMENT OF DISHEVELLED-3 PHOSPHORYLATION STATUS BY MASS SPECTROMETRY
Authors HANÁKOVÁ, Kateřina (203 Czech Republic, belonging to the institution), David POTĚŠIL (203 Czech Republic, belonging to the institution), Ondřej BERNATÍK (203 Czech Republic, belonging to the institution), Igor ČERVENKA (703 Slovakia, belonging to the institution), Matěj RÁDSETOULAL (203 Czech Republic, belonging to the institution), Vítězslav BRYJA (203 Czech Republic, belonging to the institution) and Zbyněk ZDRÁHAL (203 Czech Republic, guarantor, belonging to the institution).
Edition HUNGARIAN JOURNAL OF INDUSTRY AND CHEMISTRY, 2018, 0133-0276.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10406 Analytical chemistry
Country of publisher Poland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.084 in 2002
RIV identification code RIV/00216224:14740/18:00101409
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1515/hjic-2018-0002
UT WoS 000440079700002
Keywords in English phosphorylation; Dishevelled 3; mass spectrometry; CK1 epsilon; NEK2
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 13/3/2019 18:53.
Abstract
The focus of this paper is the human Dishevelled 3 protein (hDvl3), an essential component of the Wnt signalling pathway that contributes to their regulation. Mass spectrometry-based analysis of hDvl3 phosphorylations induced by eight associated kinases was performed revealing several dozens of phosphorylation sites. The main outcome of this study was the description of Dvl phosphorylation "patterns" induced by individual kinases.
Links
GA15-21789S, research and development projectName: Dishevelled - identifikace základních koordinát
Investor: Czech Science Foundation
LM2015043, research and development projectName: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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