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@article{1479816,
author = {Andrašinová, Tereza and Vagaská, Eva and Kopáčik, Roman and Šrotová, Iva and Vlčková, Eva and Dušek, Ladislav and Bednařík, Josef and Adamová, Blanka},
article_location = {Philadelphia},
article_number = {1},
doi = {http://dx.doi.org/10.1097/AJP.0000000000000653},
keywords = {Neuropathic pain; low back pain; quantitative sensory testing},
language = {eng},
issn = {0749-8047},
journal = {The Clinical Journal of Pain},
title = {Evaluation of the Neuropathic Component of Chronic Low Back Pain},
url = {http://dx.doi.org/10.1097/AJP.0000000000000653},
volume = {35},
year = {2019}
}
TY - JOUR
ID - 1479816
AU - Andrašinová, Tereza - Vagaská, Eva - Kopáčik, Roman - Šrotová, Iva - Vlčková, Eva - Dušek, Ladislav - Bednařík, Josef - Adamová, Blanka
PY - 2019
TI - Evaluation of the Neuropathic Component of Chronic Low Back Pain
JF - The Clinical Journal of Pain
VL - 35
IS - 1
SP - 7-17
EP - 7-17
PB - LIPPINCOTT WILLIAMS & WILKINS
SN - 07498047
KW - Neuropathic pain
KW - low back pain
KW - quantitative sensory testing
UR - http://dx.doi.org/10.1097/AJP.0000000000000653
L2 - http://dx.doi.org/10.1097/AJP.0000000000000653
N2 - Objectives: Assessment of neuropathic pain in chronic low back syndromes is important. However, there is currently no gold standard for its diagnosis. The aim of this observational cross-sectional study was to assess the neuropathic component of pain in various chronic low back pain syndromes using a range of diagnostic tests. Materials and Methods: Included in this study were 63 patients with chronic axial low back pain (ALBP), 48 patients with chronic radicular syndromes (CRS) comprising 23 with discogenic compression (CDRS) and 25 with lumbar spinal stenosis (LSS), and 74 controls. PainDETECT questionnaire (PDQ), quantitative sensory testing (QST), and skin biopsy with evaluation of intraepidermal nerve fiber density (IENFD) were used to assess the neuropathic pain component. Results: Positive PDQ (>= 19) was obtained more frequently in patients with CDRS and LSS (26.1% and 12.0%, respectively) compared with patients with ALBP (1.6%, P<0.001). The proportion of patients with sensory loss confirmed by QST was lowest in the ALBP subgroup (23.8%) compared with CDRS (47.8%), and LSS (68.0%) subgroups (P<0.001). A reduction in IENFD was disclosed in a proportion of up to 52.0% of affected roots in patients with CRS. Discussion: Neuropathic pain is quite frequent in CRS, and QST reveals sensory loss as a frequent abnormality in patients with CRS. Using a cut-off value of 19, PDQ identified a neuropathic component in a relatively low proportion of patients with CRS. CRS may be associated with a reduction in IENFD.
ER -
ANDRAŠINOVÁ, Tereza, Eva VAGASKÁ, Roman KOPÁČIK, Iva ŠROTOVÁ, Eva VLČKOVÁ, Ladislav DUŠEK, Josef BEDNAŘÍK and Blanka ADAMOVÁ. Evaluation of the Neuropathic Component of Chronic Low Back Pain. \textit{The Clinical Journal of Pain}. Philadelphia: LIPPINCOTT WILLIAMS \&{} WILKINS, 2019, vol.~35, No~1, p.~7-17. ISSN~0749-8047. Available from: https://dx.doi.org/10.1097/AJP.0000000000000653.
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