Detailed Information on Publication Record
2019
Evaluation of the Neuropathic Component of Chronic Low Back Pain
ANDRAŠINOVÁ, Tereza, Eva VAGASKÁ, Roman KOPÁČIK, Iva ŠROTOVÁ, Eva VLČKOVÁ et. al.Basic information
Original name
Evaluation of the Neuropathic Component of Chronic Low Back Pain
Authors
ANDRAŠINOVÁ, Tereza (203 Czech Republic, belonging to the institution), Eva VAGASKÁ (703 Slovakia, belonging to the institution), Roman KOPÁČIK (703 Slovakia, belonging to the institution), Iva ŠROTOVÁ (203 Czech Republic, belonging to the institution), Eva VLČKOVÁ (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution) and Blanka ADAMOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
The Clinical Journal of Pain, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2019, 0749-8047
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30210 Clinical neurology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 2.893
RIV identification code
RIV/00216224:14110/19:00108962
Organization unit
Faculty of Medicine
UT WoS
000453529900002
Keywords in English
Neuropathic pain; low back pain; quantitative sensory testing
Tags
International impact, Reviewed
Změněno: 31/3/2020 22:20, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
Objectives: Assessment of neuropathic pain in chronic low back syndromes is important. However, there is currently no gold standard for its diagnosis. The aim of this observational cross-sectional study was to assess the neuropathic component of pain in various chronic low back pain syndromes using a range of diagnostic tests. Materials and Methods: Included in this study were 63 patients with chronic axial low back pain (ALBP), 48 patients with chronic radicular syndromes (CRS) comprising 23 with discogenic compression (CDRS) and 25 with lumbar spinal stenosis (LSS), and 74 controls. PainDETECT questionnaire (PDQ), quantitative sensory testing (QST), and skin biopsy with evaluation of intraepidermal nerve fiber density (IENFD) were used to assess the neuropathic pain component. Results: Positive PDQ (>= 19) was obtained more frequently in patients with CDRS and LSS (26.1% and 12.0%, respectively) compared with patients with ALBP (1.6%, P<0.001). The proportion of patients with sensory loss confirmed by QST was lowest in the ALBP subgroup (23.8%) compared with CDRS (47.8%), and LSS (68.0%) subgroups (P<0.001). A reduction in IENFD was disclosed in a proportion of up to 52.0% of affected roots in patients with CRS. Discussion: Neuropathic pain is quite frequent in CRS, and QST reveals sensory loss as a frequent abnormality in patients with CRS. Using a cut-off value of 19, PDQ identified a neuropathic component in a relatively low proportion of patients with CRS. CRS may be associated with a reduction in IENFD.
Links
| MUNI/A/1072/2017, interní kód MU |
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| MUNI/A/1419/2018, interní kód MU |
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