JANOUTOVA, J., P. AMBROZ, M. KOVALOVA, O. MACHACZKA, K. NEMCEK, A. ZATLOUKALOVA, E. MRAZKOVA, O. KOSTA, Alice HÁLOVÁ, Ladislav HOSÁK and Vladimír JANOUT. Epidemiology of mild cognitive impairment. Ceska a slovenska neurologie a neurochirurgie. Praha: Česká lékařská společnost J.E. Purkyně, 2018, vol. 81, No 3, p. 284-289. ISSN 1210-7859. Available from: https://dx.doi.org/10.14735/amcsnn2018284.
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Basic information
Original name Epidemiology of mild cognitive impairment
Name (in English) Epidemiology of mild cognitive impairment
Authors JANOUTOVA, J. (203 Czech Republic), P. AMBROZ (203 Czech Republic), M. KOVALOVA (203 Czech Republic), O. MACHACZKA (203 Czech Republic), K. NEMCEK (203 Czech Republic), A. ZATLOUKALOVA (203 Czech Republic), E. MRAZKOVA (203 Czech Republic), O. KOSTA (203 Czech Republic), Alice HÁLOVÁ (203 Czech Republic, belonging to the institution), Ladislav HOSÁK (203 Czech Republic) and Vladimír JANOUT (203 Czech Republic).
Edition Ceska a slovenska neurologie a neurochirurgie, Praha, Česká lékařská společnost J.E. Purkyně, 2018, 1210-7859.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30302 Epidemiology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 0.355
RIV identification code RIV/00216224:14310/18:00105132
Organization unit Faculty of Science
Doi http://dx.doi.org/10.14735/amcsnn2018284
UT WoS 000433570400007
Keywords in English mild cognitive impairment; dementia; epidemiology; risk factors
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Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 23/4/2024 12:59.
Abstract
Background: Mild cognitive impairment (MCI) is a transitional phase between cognitive changes in physiological aging and early dementia. The amnestic form of MCI is considered a precursor to Alzheimer's disease. The increasing number of elderly persons in the population is as sociated with an increase in the prevalence of chronic diseases including cognitive impairment and subsequent dementia. Aim: The aim of this work is to describe factors influencing the decrease of cognitive functions and development of MCI and subsequent dementia. Hypertension, hypercholesterolemia, diabetes mellitus and obesity are more frequent during middle age and contribute to the risk of dementia in older age through various cerebrovascular diseases and inflammatory/neurodegenerative mechanisms. At the same time, impaired cognitive functioning is associated with behavioral and psychosocial factors. The article provides an overview of potential vascular, behavioral and psychosocial risk factors for MCI and dementia. Conclusion: Knowledge of the risk factors for MCI and dementia will allow early prevention and effective therapy of these serious diseases.
Abstract (in English)
Background: Mild cognitive impairment (MCI) is a transitional phase between cognitive changes in physiological aging and early dementia. The amnestic form of MCI is considered a precursor to Alzheimer's disease. The increasing number of elderly persons in the population is as sociated with an increase in the prevalence of chronic diseases including cognitive impairment and subsequent dementia. Aim: The aim of this work is to describe factors influencing the decrease of cognitive functions and development of MCI and subsequent dementia. Hypertension, hypercholesterolemia, diabetes mellitus and obesity are more frequent during middle age and contribute to the risk of dementia in older age through various cerebrovascular diseases and inflammatory/neurodegenerative mechanisms. At the same time, impaired cognitive functioning is associated with behavioral and psychosocial factors. The article provides an overview of potential vascular, behavioral and psychosocial risk factors for MCI and dementia. Conclusion: Knowledge of the risk factors for MCI and dementia will allow early prevention and effective therapy of these serious diseases.
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