Detailed Information on Publication Record
2018
Pyrazolotriazines as inhibitors of nucleases
DAMBORSKÝ, Jiří, Fedor NIKULENKOV, Alexandra SISÁKOVÁ, Štěpán HAVEL, Lumír KREJČÍ et. al.Basic information
Original name
Pyrazolotriazines as inhibitors of nucleases
Authors
DAMBORSKÝ, Jiří (203 Czech Republic, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution), Alexandra SISÁKOVÁ (703 Slovakia, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Lumír KREJČÍ (203 Czech Republic, belonging to the institution), Benoit Jean-Pierre CARBAIN (250 France, belonging to the institution), Jan BREZOVSKÝ (203 Czech Republic, belonging to the institution), Lukáš DANIEL (203 Czech Republic, belonging to the institution) and Kamil PARUCH (203 Czech Republic, belonging to the institution)
Edition
Number: US 9969741 B2, Publisher: USPTO, Place of publication: USA, Owner's name: Masarykova univerzita, 2018
Other information
Language
English
Type of outcome
Patent
Field of Study
10400 1.4 Chemical sciences
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
RIV identification code
RIV/00216224:14310/18:00105284
Organization unit
Faculty of Science
Keywords in English
inhibitor; nuclease; DNA repair; pyrazolotriazine; MUS81
Tags
Změněno: 13/4/2019 15:10, doc. Mgr. Kamil Paruch, Ph.D.
Abstract
V originále
The present invention relates to substituted heterocycles as inhibitors of nudeases MUS81 and MRE11, pharmaceutical compositions containing the compounds, and pharmaceutical use of the compounds and compositions in the treatment of the diseases such as, for example, cancer.
Links
| LM2015063, research and development project |
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| MUNI/M/1894/2014, interní kód MU |
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