SVAČINOVÁ, Jana, Katarína ONDRUŠOVÁ, Michal JAVORKA, Zuzana NOVÁKOVÁ and Marie NOVÁKOVÁ. Influence of compression aids on baroreflex in patients after cervical spinal cord injury. In Germaine CORNELISSEN, Jarmila SIEGELOVÁ a Petr DOBŠÁK. Noninvasive methods in cardiology 2018. first edition. Nové Město nad Metují: Masaryk University, 2018, p. 63-70. ISBN 978-80-210-9109-2.
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Basic information
Original name Influence of compression aids on baroreflex in patients after cervical spinal cord injury
Name in Czech Porucha regulace krevního tlaku u pacientů s poraněním míchy
Authors SVAČINOVÁ, Jana (203 Czech Republic, guarantor, belonging to the institution), Katarína ONDRUŠOVÁ (703 Slovakia, belonging to the institution), Michal JAVORKA (703 Slovakia), Zuzana NOVÁKOVÁ (203 Czech Republic, belonging to the institution) and Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution).
Edition first edition. Nové Město nad Metují, Noninvasive methods in cardiology 2018, p. 63-70, 8 pp. 2018.
Publisher Masaryk University
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14110/18:00105522
Organization unit Faculty of Medicine
ISBN 978-80-210-9109-2
Keywords (in Czech) Poranění krční míchy; ortostatická hypotenze; baroreflex; kompresní pomůcky
Keywords in English Cervical spinal cord injury; orthostatic hypotension; baroreflex; compression aids
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 2/5/2019 14:43.
Abstract
Introduction: Patients after cervical spinal cord injury (cSCI) often suffer from orthostatic hypotension (OH). Although vagal cardiac chronotropic effect is preserved in cSCI, baroreflex vascular tone regulation is impaired due to interrupted sympathetic pathways below the cSCI level. Patients usually use compression aids (CA, e.g. stockings, abdominal corset) to mitigate blood pressure (BP) drop during orthostasis. This study aimed to assess the influence of CA on baroreflex function in cSCI patients during orthostasis. Methods: BP was continuously recorded in 9 cSCI patients during passive orthostasis without and with CA. Beat-to-beat systolic blood pressure (SBP) and inter-beat intervals (IBI) sequences were obtained from continuous non-invasive BP recording. Pulse pressure (PP) was evaluated as a mean of beat-to-beat differences between SBP and diastolic pressures. Closed loop of SBP IBI interaction was mathematically opened by bivariate autoregressive model; causal coherence (a measure of IBI and SBP synchronization) and gain estimating baroreflex sensitivity (BRS) were calculated in baroreflex direction (from SBP to IBI). Results: When CA were applied, coherence and PP were significantly increased as compared to orthostasis without CA (p < 0.05). CA application was also associated with an increase of BRS (borderline significant; p = 0.059). Patients reported less OH symptoms when wearing CA. Conclusion: Use of CA increased venous return and consequently stroke volume expressed as an increase of PP in this study. This probably prevented the baroreflex sensitivity decrease during orthostasis. We suppose that positive influence of CA on blood pressure regulation during orthostasis weakened OH symptoms in cSCI.
Links
MUNI/A/1157/2017, interní kód MUName: Kardiovaskulární systém napříč obory - od molekulární diagnostiky po klinická vyšetření (Acronym: KADIMOKLIN)
Investor: Masaryk University, Category A
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