Analytical and bioanalytical assessments of organic
micropollutants in the Bosna River using a combination of
passive sampling, bioassays and multi-residue analysis

J 2019

Analytical and bioanalytical assessments of organic micropollutants in the Bosna River using a combination of passive sampling, bioassays and multi-residue analysis

TOUŠOVÁ, Zuzana, Branislav VRANA, Marie SMUTNÁ, Jiří NOVÁK, Veronika KLUČÁROVÁ et. al.

Basic information

Original name

Analytical and bioanalytical assessments of organic micropollutants in the Bosna River using a combination of passive sampling, bioassays and multi-residue analysis

Authors

TOUŠOVÁ, Zuzana (203 Czech Republic, belonging to the institution), Branislav VRANA (703 Slovakia, belonging to the institution), Marie SMUTNÁ (203 Czech Republic, belonging to the institution), Jiří NOVÁK (203 Czech Republic, belonging to the institution), Veronika KLUČÁROVÁ (703 Slovakia), Roman GRABIC (203 Czech Republic), Jaroslav SLOBODNÍK (703 Slovakia), John Paul GIESY (124 Canada) and Klára HILSCHEROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Science of the Total Environment, Amsterdam, Elsevier Science, 2019, 0048-9697

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Full Text

Impact factor

Impact factor: 6.551

RIV identification code

RIV/00216224:14310/19:00109027

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.scitotenv.2018.08.336

UT WoS

000447092700160

Keywords in English

Contaminants of emerging concern - passive sampling; In vitro bioassay - endocrine disruption; Hazard profiling - water quality monitoring

Abstract

V originále

Complex mixtures of contaminants from multiple sources, including agriculture, industry or wastewater enter aquatic environments and might pose hazards or risks to humans or wildlife. Targeted analyses of a few priority substances provide limited information about water quality. In this study, a combined chemical and effect screening of water quality in the River Bosna, in Bosnia and Herzegovina was carried out, with focus on occurrence and effects of contaminants of emerging concern. Chemicals in water were sampled at 10 sites along the Bosna River by use of passive sampling. The combination of semipermeable membrane devices (SPMDs) and polar organic chemical integrative samplers (POCIS) enabled sampling of a broad range of contaminants from hydrophobic (PAHs, PCBs, OCPs) to hydrophilic compounds (pesticides, pharmaceuticals and hormones), which were determined by use of GC-MS and LC-MS (MS). In vitro, cell-based bioassays were applied to assess (anti) androgenic, estrogenic and dioxin-like potencies of extracts of the samplers. Of a total of 168 targeted compounds, 107 were detected at least once. Cumulative pollutant concentrations decreased downstream from the city of Sarajevo, which was identified as the major source of organic pollutants in the area. Responses in all bioassays were observed for samples from all sites. In general, estrogenicity could be well explained by analysis of target estrogens, while the drivers of the other observed effects remained largely unknown. Profiling of hazard quotients identified two sites downstream of Sarajevo as hotspots of biological potency. Risk assessment of detected compounds revealed, that 7 compounds (diazinon, diclofenac, 17 beta-estradiol, estrone, benzo[k] fluoranthene, fluoranthene and benzo[k] fluoranthene) might pose risks to aquatic biota in the Bosna River. The study brings unique results of a complex water quality assessment in a region with an insufficient water treatment infrastructure.

Links

603437, interní kód MU

Name: SOLUTIONS - Solutions for present and future emerging pollutants in land and water resources management (Acronym: SOLUTIONS)

Investor: European Union, Cooperation

Citovat

TOUŠOVÁ, Zuzana, Branislav VRANA, Marie SMUTNÁ, Jiří NOVÁK, Veronika KLUČÁROVÁ, Roman GRABIC, Jaroslav SLOBODNÍK, John Paul GIESY and Klára HILSCHEROVÁ. Analytical and bioanalytical assessments of organic micropollutants in the Bosna River using a combination of passive sampling, bioassays and multi-residue analysis. Science of the Total Environment. Amsterdam: Elsevier Science, 2019, vol. 650, February, p. 1599-1612. ISSN 0048-9697. Available from: https://dx.doi.org/10.1016/j.scitotenv.2018.08.336.

@article{1488444,
   author = {Toušová, Zuzana and Vrana, Branislav and Smutná, Marie and Novák, Jiří and Klučárová, Veronika and Grabic, Roman and Slobodník, Jaroslav and Giesy, John Paul and Hilscherová, Klára},
   article_location = {Amsterdam},
   article_number = {February},
   doi = {http://dx.doi.org/10.1016/j.scitotenv.2018.08.336},
   keywords = {Contaminants of emerging concern - passive sampling; In vitro bioassay - endocrine disruption; Hazard profiling - water quality monitoring},
   language = {eng},
   issn = {0048-9697},
   journal = {Science of the Total Environment},
   title = {Analytical and bioanalytical assessments of organic micropollutants in the Bosna River using a combination of passive sampling, bioassays and multi-residue analysis},
   url = {https://www.sciencedirect.com/science/article/pii/S0048969718333072?via%3Dihub},
   volume = {650},
   year = {2019}
}

TY  - JOUR
ID  - 1488444
AU  - Toušová, Zuzana - Vrana, Branislav - Smutná, Marie - Novák, Jiří - Klučárová, Veronika - Grabic, Roman - Slobodník, Jaroslav - Giesy, John Paul - Hilscherová, Klára
PY  - 2019
TI  - Analytical and bioanalytical assessments of organic micropollutants in the Bosna River using a combination of passive sampling, bioassays and multi-residue analysis
JF  - Science of the Total Environment
VL  - 650
IS  - February
SP  - 1599-1612
EP  - 1599-1612
PB  - Elsevier Science
SN  - 00489697
KW  - Contaminants of emerging concern - passive sampling
KW  - In vitro bioassay - endocrine disruption
KW  - Hazard profiling - water quality monitoring
UR  - https://www.sciencedirect.com/science/article/pii/S0048969718333072?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0048969718333072?via%3Dihub
N2  - Complex mixtures of contaminants from multiple sources, including agriculture, industry or wastewater enter aquatic environments and might pose hazards or risks to humans or wildlife. Targeted analyses of a few priority substances provide limited information about water quality. In this study, a combined chemical and effect screening of water quality in the River Bosna, in Bosnia and Herzegovina was carried out, with focus on occurrence and effects of contaminants of emerging concern. Chemicals in water were sampled at 10 sites along the Bosna River by use of passive sampling. The combination of semipermeable membrane devices (SPMDs) and polar organic chemical integrative samplers (POCIS) enabled sampling of a broad range of contaminants from hydrophobic (PAHs, PCBs, OCPs) to hydrophilic compounds (pesticides, pharmaceuticals and hormones), which were determined by use of GC-MS and LC-MS (MS). In vitro, cell-based bioassays were applied to assess (anti) androgenic, estrogenic and dioxin-like potencies of extracts of the samplers. Of a total of 168 targeted compounds, 107 were detected at least once. Cumulative pollutant concentrations decreased downstream from the city of Sarajevo, which was identified as the major source of organic pollutants in the area. Responses in all bioassays were observed for samples from all sites. In general, estrogenicity could be well explained by analysis of target estrogens, while the drivers of the other observed effects remained largely unknown. Profiling of hazard quotients identified two sites downstream of Sarajevo as hotspots of biological potency. Risk assessment of detected compounds revealed, that 7 compounds (diazinon, diclofenac, 17 beta-estradiol, estrone, benzo[k] fluoranthene, fluoranthene and benzo[k] fluoranthene) might pose risks to aquatic biota in the Bosna River. The study brings unique results of a complex water quality assessment in a region with an insufficient water treatment infrastructure.
ER  -

TOUŠOVÁ, Zuzana, Branislav VRANA, Marie SMUTNÁ, Jiří NOVÁK, Veronika KLUČÁROVÁ, Roman GRABIC, Jaroslav SLOBODNÍK, John Paul GIESY and Klára HILSCHEROVÁ. Analytical and bioanalytical assessments of organic micropollutants in the Bosna River using a combination of passive sampling, bioassays and multi-residue analysis. \textit{Science of the Total Environment}. Amsterdam: Elsevier Science, 2019, vol.~650, February, p.~1599-1612. ISSN~0048-9697. Available from: https://dx.doi.org/10.1016/j.scitotenv.2018.08.336.

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