Development of early reperfusion after the first episode of
acute pulmonary embolism

J 2018

Development of early reperfusion after the first episode of acute pulmonary embolism

VÁCLAVKOVÁ, Jana, Jan MRÓZEK, Vladimír JANOVSKÝ, Pavol BINDAS, Jana PETROVÁ et. al.

Basic information

Original name

Development of early reperfusion after the first episode of acute pulmonary embolism

Authors

VÁCLAVKOVÁ, Jana (203 Czech Republic, guarantor), Jan MRÓZEK (203 Czech Republic), Vladimír JANOVSKÝ (203 Czech Republic), Pavol BINDAS (203 Czech Republic), Jana PETROVÁ (203 Czech Republic), Luboš KRAUS (203 Czech Republic), Michal SVOBODA (203 Czech Republic, belonging to the institution) and Pavel JANSA (203 Czech Republic)

Edition

cor et Vasa, AMSTERDAM, ELSEVIER SCIENCE BV, 2018, 0010-8650

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/18:00105796

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.crvasa.2017.12.014

UT WoS

000451063200007

Keywords in English

Pulmonary embolism; Reperfusion; Chronic thromboembolic disease; Chronic thromboembolic pulmonary hypertension

Abstract

V originále

Introduction: Factors influencing the early reperfusion after pulmonary embolism (PE), with possible impact on development of chronic thromboembolic disease and chronic thromboembolic pulmonary hypertension (CTEPH), have not been completely identified yet. Study population and methods: The total of 85 patients hospitalized with the first episode of acute PE underwent a ventilation-perfusion lung scan before hospital discharge. The reperfusion was evaluated based on clinical, echocardiographic and laboratory parameters. Results: The study population consisted of 37 men and 48 women, mean age 60 years. A high-risk PE was present in 9.4% of patients, medium-risk PE in 49.4% and low-risk PE in 41.2% of patients. 26 (30.5%) of patients were diagnosed with provoked pulmonary embolism. Prior to discharge, the residual perfusion defects were detectable in 66 patients, in 18 patients the perfusion was normal. The two groups did not significantly differ in clinical, echocardiographic or laboratory parameters. Conclusion: The analysis did not identify risk factors significantly associated with the absence of early reperfusion of the PE. This points toward the need of further follow-up of patients after a PE with the aim of identifying the patients with the high risk of developing the chronic thromboembolic disease and CTEPH. (C) 2018 The Czech Society of Cardiology. Published by Elsevier Sp. z o.o. All rights reserved.

Citovat

VÁCLAVKOVÁ, Jana, Jan MRÓZEK, Vladimír JANOVSKÝ, Pavol BINDAS, Jana PETROVÁ, Luboš KRAUS, Michal SVOBODA and Pavel JANSA. Development of early reperfusion after the first episode of acute pulmonary embolism. cor et Vasa. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, vol. 60, No 6, p. "E603"-"E606", 4 pp. ISSN 0010-8650. Available from: https://dx.doi.org/10.1016/j.crvasa.2017.12.014.

@article{1489173,
   author = {Václavková, Jana and Mrózek, Jan and Janovský, Vladimír and Bindas, Pavol and Petrová, Jana and Kraus, Luboš and Svoboda, Michal and Jansa, Pavel},
   article_location = {AMSTERDAM},
   article_number = {6},
   doi = {http://dx.doi.org/10.1016/j.crvasa.2017.12.014},
   keywords = {Pulmonary embolism; Reperfusion; Chronic thromboembolic disease; Chronic thromboembolic pulmonary hypertension},
   language = {eng},
   issn = {0010-8650},
   journal = {cor et Vasa},
   title = {Development of early reperfusion after the first episode of acute pulmonary embolism},
   volume = {60},
   year = {2018}
}

TY  - JOUR
ID  - 1489173
AU  - Václavková, Jana - Mrózek, Jan - Janovský, Vladimír - Bindas, Pavol - Petrová, Jana - Kraus, Luboš - Svoboda, Michal - Jansa, Pavel
PY  - 2018
TI  - Development of early reperfusion after the first episode of acute pulmonary embolism
JF  - cor et Vasa
VL  - 60
IS  - 6
SP  - "E603"-"E606"
EP  - "E603"-"E606"
PB  - ELSEVIER SCIENCE BV
SN  - 00108650
KW  - Pulmonary embolism
KW  - Reperfusion
KW  - Chronic thromboembolic disease
KW  - Chronic thromboembolic pulmonary hypertension
N2  - Introduction: Factors influencing the early reperfusion after pulmonary embolism (PE), with possible impact on development of chronic thromboembolic disease and chronic thromboembolic pulmonary hypertension (CTEPH), have not been completely identified yet. Study population and methods: The total of 85 patients hospitalized with the first episode of acute PE underwent a ventilation-perfusion lung scan before hospital discharge. The reperfusion was evaluated based on clinical, echocardiographic and laboratory parameters. Results: The study population consisted of 37 men and 48 women, mean age 60 years. A high-risk PE was present in 9.4% of patients, medium-risk PE in 49.4% and low-risk PE in 41.2% of patients. 26 (30.5%) of patients were diagnosed with provoked pulmonary embolism. Prior to discharge, the residual perfusion defects were detectable in 66 patients, in 18 patients the perfusion was normal. The two groups did not significantly differ in clinical, echocardiographic or laboratory parameters. Conclusion: The analysis did not identify risk factors significantly associated with the absence of early reperfusion of the PE. This points toward the need of further follow-up of patients after a PE with the aim of identifying the patients with the high risk of developing the chronic thromboembolic disease and CTEPH. (C) 2018 The Czech Society of Cardiology. Published by Elsevier Sp. z o.o. All rights reserved.
ER  -

VÁCLAVKOVÁ, Jana, Jan MRÓZEK, Vladimír JANOVSKÝ, Pavol BINDAS, Jana PETROVÁ, Luboš KRAUS, Michal SVOBODA and Pavel JANSA. Development of early reperfusion after the first episode of acute pulmonary embolism. \textit{cor et Vasa}. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, vol.~60, No~6, p.~''E603''-''E606'', 4 pp. ISSN~0010-8650. Available from: https://dx.doi.org/10.1016/j.crvasa.2017.12.014.

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