Detailed Information on Publication Record
2018
Estimated dietary iodine intake as a predictor of placental size: evidence from the ELSPAC study
DOBROVOLNÁ, Julie, Markéta GRULICHOVÁ, Ondřej MIKEŠ, Filip ZLÁMAL, Tomáš PRUŠA et. al.Basic information
Original name
Estimated dietary iodine intake as a predictor of placental size: evidence from the ELSPAC study
Authors
DOBROVOLNÁ, Julie (203 Czech Republic, guarantor, belonging to the institution), Markéta GRULICHOVÁ (203 Czech Republic, belonging to the institution), Ondřej MIKEŠ (203 Czech Republic, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Tomáš PRUŠA (203 Czech Republic, belonging to the institution), Aneta POHOŘALÁ (203 Czech Republic, belonging to the institution), Lenka ANDRÝSKOVÁ (203 Czech Republic, belonging to the institution) and Hynek PIKHART (203 Czech Republic, belonging to the institution)
Edition
NUTRITION & METABOLISM, LONDON, BIOMED CENTRAL LTD, 2018, 1743-7075
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30308 Nutrition, Dietetics
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.599
RIV identification code
RIV/00216224:14310/18:00105834
Organization unit
Faculty of Science
UT WoS
000422983500001
Keywords in English
Iodine intake; Placental weight; Birth weight/placental weight; Birth outcome; ELSPAC
Tags
International impact, Reviewed
Změněno: 23/4/2024 14:06, Mgr. Michal Petr
Abstract
V originále
Background: The relationship between low iodine status and pregnancy-associated comorbidities has been known for decades. The relationship between iodine intake and placental pathologies is, however, far less clear. This study was designed to examine the relationship between dietary iodine intake and placental size while also focusing on typical adverse pregnancy outcomes. Method: The dietary iodine intake of 4711 pregnant women enrolled in the Czech part of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) in 1990-1991 was established using a 145-item food frequency questionnaire. Multivariate linear regression models were used to estimate the relationship between dietary iodine intake during pregnancy and placental weight. Additional models were constructed to investigate the relationship between estimated dietary iodine intake and adverse birth outcomes. Results: The estimated average iodine intake in the ELSPAC cohort was 106.6 mu g/day. In the fully adjusted model, estimated dietary iodine intake was found to be significantly negatively associated with placental weight (beta = -0.025, 95% CI: -0.044; -0.006, p = 0.011). Moreover, estimated dietary iodine intake was found to be significantly positively associated with the birth weight /placental weight ratio in the fully adjusted model (beta = -0.024, 95% CI: 0.004; 0.043, p = 0.016). Conclusions: This study provides evidence of a relationship between estimated dietary iodine intake and placental weight and the birth weight /placental weight ratio. Additional research is warranted to provide more insight into the role of iodine in early as well as late placentation.
Links
| EF15_003/0000469, research and development project |
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| LM2015051, research and development project |
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