NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS
DISEASE

J 2018

NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS DISEASE

DOUBKOVÁ, Martina, Jitka HAUSNEROVÁ, Ondřej VÝŠKA, Svatopluk RICHTER, Zdeněk MERTA et. al.

Basic information

Original name

NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS DISEASE

Authors

DOUBKOVÁ, Martina (203 Czech Republic, guarantor, belonging to the institution), Jitka HAUSNEROVÁ (203 Czech Republic), Ondřej VÝŠKA (203 Czech Republic), Svatopluk RICHTER (203 Czech Republic, belonging to the institution) and Zdeněk MERTA (203 Czech Republic, belonging to the institution)

Edition

Sarcoidosis Vasculitis and Diffuse Lung Diseases, Fidenza, Mattioli 1885, 2018, 1124-0490

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30203 Respiratory systems

Country of publisher

Italy

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.889

RIV identification code

RIV/00216224:14110/18:00105961

Organization unit

Faculty of Medicine

UT WoS

000452167600014

Keywords in English

differential diagnosis; histopathological diagnosis; necrotising sarcoid granulomatosis

Abstract

V originále

Introduction: Necrotizing sarcoid granulomatosis (NSG) is a very rare disease of unknown etiology characterized by sarcoid-like granulomas, vasculitis and necrosis in pulmonary and extrapulmonary localizations. Case report: We describe a case of a 34-year-old Caucasian male with fever, pleural pain, and nodular pulmonary opacities on chest radiograph. Histological examination of the lung tissue confirmed NSG. Diagnostically, infectious causes, vasculitis, and malignancy were excluded. A tendency to partial regression was observed, without the need for corticosteroid treatment. Conclusion: NSG is a rare disease which must be distinguished from other systemic diseases including vasculitides. The key to diagnosis, emphasized in our paper, is the histopathological finding. The course of NSG is similar to sarcoidosis. Corticosteroids are considered the treatment of choice, but the disease exhibits a tendency towards spontaneous regression.

Citovat

DOUBKOVÁ, Martina, Jitka HAUSNEROVÁ, Ondřej VÝŠKA, Svatopluk RICHTER and Zdeněk MERTA. NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS DISEASE. Sarcoidosis Vasculitis and Diffuse Lung Diseases. Fidenza: Mattioli 1885, 2018, vol. 35, No 4, p. 395-398. ISSN 1124-0490.

@article{1491934,
   author = {Doubková, Martina and Hausnerová, Jitka and Výška, Ondřej and Richter, Svatopluk and Merta, Zdeněk},
   article_location = {Fidenza},
   article_number = {4},
   keywords = {differential diagnosis; histopathological diagnosis; necrotising sarcoid granulomatosis},
   language = {eng},
   issn = {1124-0490},
   journal = {Sarcoidosis Vasculitis and Diffuse Lung Diseases},
   title = {NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS DISEASE},
   volume = {35},
   year = {2018}
}

TY  - JOUR
ID  - 1491934
AU  - Doubková, Martina - Hausnerová, Jitka - Výška, Ondřej - Richter, Svatopluk - Merta, Zdeněk
PY  - 2018
TI  - NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS DISEASE
JF  - Sarcoidosis Vasculitis and Diffuse Lung Diseases
VL  - 35
IS  - 4
SP  - 395-398
EP  - 395-398
PB  - Mattioli 1885
SN  - 11240490
KW  - differential diagnosis
KW  - histopathological diagnosis
KW  - necrotising sarcoid granulomatosis
N2  - Introduction: Necrotizing sarcoid granulomatosis (NSG) is a very rare disease of unknown etiology characterized by sarcoid-like granulomas, vasculitis and necrosis in pulmonary and extrapulmonary localizations. Case report: We describe a case of a 34-year-old Caucasian male with fever, pleural pain, and nodular pulmonary opacities on chest radiograph. Histological examination of the lung tissue confirmed NSG. Diagnostically, infectious causes, vasculitis, and malignancy were excluded. A tendency to partial regression was observed, without the need for corticosteroid treatment. Conclusion: NSG is a rare disease which must be distinguished from other systemic diseases including vasculitides. The key to diagnosis, emphasized in our paper, is the histopathological finding. The course of NSG is similar to sarcoidosis. Corticosteroids are considered the treatment of choice, but the disease exhibits a tendency towards spontaneous regression.
ER  -

DOUBKOVÁ, Martina, Jitka HAUSNEROVÁ, Ondřej VÝŠKA, Svatopluk RICHTER and Zdeněk MERTA. NECROTISING SARCOID GRANULOMATOSIS. A RARE GRANULOMATOUS DISEASE. \textit{Sarcoidosis Vasculitis and Diffuse Lung Diseases}. Fidenza: Mattioli 1885, 2018, vol.~35, No~4, p.~395-398. ISSN~1124-0490.

Detailed Information on Publication Record