CLL cells cumulate genetic aberrations prior to the first
therapy even in outwardly inactive disease phase

J 2019

CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase

HERNANDEZ-SANCHEZ, M., Jana KOTAŠKOVÁ, A.E. RODRIGUEZ, Lenka RADOVÁ, D. TAMBORERO et. al.

Basic information

Original name

CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase

Authors

HERNANDEZ-SANCHEZ, M. (724 Spain), Jana KOTAŠKOVÁ (203 Czech Republic, belonging to the institution), A.E. RODRIGUEZ (724 Spain), Lenka RADOVÁ (203 Czech Republic, belonging to the institution), D. TAMBORERO (724 Spain), M. ABAIGAR (724 Spain), Karla PLEVOVÁ (203 Czech Republic, belonging to the institution), R. BENITO (724 Spain), Nikola TOM (203 Czech Republic, belonging to the institution), M. QUIJADA-ALAMO (724 Spain), Vasileios BIKOS (300 Greece, belonging to the institution), A.A. MARTIN (724 Spain), Karol PÁL (703 Slovakia, belonging to the institution), A. DE COCA (724 Spain), Michael DOUBEK (203 Czech Republic, belonging to the institution), N. LOPEZ-BIGAS (724 Spain), J.M. HERNANDEZ-RIVAS (724 Spain) and Šárka POSPÍŠILOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Leukemia, London, Nature Publishing Group, 2019, 0887-6924

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30204 Oncology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 8.665

RIV identification code

RIV/00216224:14740/19:00109079

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1038/s41375-018-0255-1

UT WoS

000457857300023

Keywords in English

CLL - genetic aberrations - NGS - WES

Abstract

V originále

CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase. CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase. CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase.

Links

EF16_013/0001634, research and development project

Name: Národní centrum lékařské genomiky - modernizace infrastruktury a výzkum genetické variability populace

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/A/0968/2017, interní kód MU

Name: Nové přístupy ve výzkumu, diagnostice a terapii hematologických malignit V (Acronym: VýDiTeHeMA V)

Investor: Masaryk University, Category A

7E13008, research and development project

Name: Next Generation Sequencing Platform for Targeted Personalized Therapy of Leukemia (Acronym: NGS-PTL)

Investor: Ministry of Education, Youth and Sports of the CR

90091, large research infrastructures

Name: NCMG

Citovat

HERNANDEZ-SANCHEZ, M., Jana KOTAŠKOVÁ, A.E. RODRIGUEZ, Lenka RADOVÁ, D. TAMBORERO, M. ABAIGAR, Karla PLEVOVÁ, R. BENITO, Nikola TOM, M. QUIJADA-ALAMO, Vasileios BIKOS, A.A. MARTIN, Karol PÁL, A. DE COCA, Michael DOUBEK, N. LOPEZ-BIGAS, J.M. HERNANDEZ-RIVAS and Šárka POSPÍŠILOVÁ. CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase (CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase.). Leukemia. London: Nature Publishing Group, 2019, vol. 33, No 2, p. 518-522. ISSN 0887-6924. Available from: https://dx.doi.org/10.1038/s41375-018-0255-1.

@article{1492291,
   author = {HernandezandSanchez, M. and Kotašková, Jana and Rodriguez, A.E. and Radová, Lenka and Tamborero, D. and Abaigar, M. and Plevová, Karla and Benito, R. and Tom, Nikola and QuijadaandAlamo, M. and Bikos, Vasileios and Martin, A.A. and Pál, Karol and de Coca, A. and Doubek, Michael and LopezandBigas, N. and HernandezandRivas, J.M. and Pospíšilová, Šárka},
   article_location = {London},
   article_number = {2},
   doi = {http://dx.doi.org/10.1038/s41375-018-0255-1},
   keywords = {CLL - genetic aberrations - NGS - WES},
   language = {eng},
   issn = {0887-6924},
   journal = {Leukemia},
   title = {CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase},
   url = {https://www.nature.com/articles/s41375-018-0255-1},
   volume = {33},
   year = {2019}
}

TY  - JOUR
ID  - 1492291
AU  - Hernandez-Sanchez, M. - Kotašková, Jana - Rodriguez, A.E. - Radová, Lenka - Tamborero, D. - Abaigar, M. - Plevová, Karla - Benito, R. - Tom, Nikola - Quijada-Alamo, M. - Bikos, Vasileios - Martin, A.A. - Pál, Karol - de Coca, A. - Doubek, Michael - Lopez-Bigas, N. - Hernandez-Rivas, J.M. - Pospíšilová, Šárka
PY  - 2019
TI  - CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase
JF  - Leukemia
VL  - 33
IS  - 2
SP  - 518-522
EP  - 518-522
PB  - Nature Publishing Group
SN  - 08876924
KW  - CLL - genetic aberrations - NGS - WES
UR  - https://www.nature.com/articles/s41375-018-0255-1
L2  - https://www.nature.com/articles/s41375-018-0255-1
N2  - CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase. CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase. CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase.
ER  -

HERNANDEZ-SANCHEZ, M., Jana KOTAŠKOVÁ, A.E. RODRIGUEZ, Lenka RADOVÁ, D. TAMBORERO, M. ABAIGAR, Karla PLEVOVÁ, R. BENITO, Nikola TOM, M. QUIJADA-ALAMO, Vasileios BIKOS, A.A. MARTIN, Karol PÁL, A. DE COCA, Michael DOUBEK, N. LOPEZ-BIGAS, J.M. HERNANDEZ-RIVAS and Šárka POSPÍŠILOVÁ. CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase (CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase.). \textit{Leukemia}. London: Nature Publishing Group, 2019, vol.~33, No~2, p.~518-522. ISSN~0887-6924. Available from: https://dx.doi.org/10.1038/s41375-018-0255-1.

Detailed Information on Publication Record