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@article{1494597,
author = {Vrbová, Markéta and Dorociaková, Petra and Vyškovský, Roman and Murinova Palkovicova, Lubica and Čižnár, Peter and Rausova, Katarina and McNabb, Scott J. N. and Reichrtova, Eva and Budinská, Eva and Thon, Vojtěch},
article_location = {New York},
article_number = {9},
doi = {http://dx.doi.org/10.1007/s00431-018-3188-9},
keywords = {Allergy; Asthma; Atopic dermatitis; Atopic march; Questionnaire; Rhino conjunctivitis},
language = {eng},
issn = {0340-6199},
journal = {European journal of pediatrics},
title = {Dynamics of allergy development during the first 5 years of life},
url = {https://link.springer.com/article/10.1007%2Fs00431-018-3188-9},
volume = {177},
year = {2018}
}
TY - JOUR
ID - 1494597
AU - Vrbová, Markéta - Dorociaková, Petra - Vyškovský, Roman - Murinova Palkovicova, Lubica - Čižnár, Peter - Rausova, Katarina - McNabb, Scott J. N. - Reichrtova, Eva - Budinská, Eva - Thon, Vojtěch
PY - 2018
TI - Dynamics of allergy development during the first 5 years of life
JF - European journal of pediatrics
VL - 177
IS - 9
SP - 1317-1325
EP - 1317-1325
PB - Springer
SN - 03406199
KW - Allergy
KW - Asthma
KW - Atopic dermatitis
KW - Atopic march
KW - Questionnaire
KW - Rhino conjunctivitis
UR - https://link.springer.com/article/10.1007%2Fs00431-018-3188-9
L2 - https://link.springer.com/article/10.1007%2Fs00431-018-3188-9
N2 - Allergic diseases have increased in developed countries during the past decades. A cohort of Slovak children was followed from birth to track allergic symptoms dynamics in early childhood. Information on allergic symptoms (atopic dermatitis = AD, rhino conjunctivitis = RC, wheezing = Wh, urticaria = Ur) and food allergies among children was based on clinical evaluation of children by allergists at three developmental stages (infant, toddler, preschool). Out of 320 cases of allergies, 64 infants, 145 toddlers, and 195 preschool children suffered from AD, RC, Wh, Ur, or their combinations (i.e., significant increase with age, p < 0.001). AD first appeared in infants, Wh and/or RC rose mainly in toddlers, and Ur among preschool children. AD in infants or toddlers disappeared in the subsequent developmental stage in approximately one third of all cases. Single AD persistence without remission or extension was not common and accounted only for 6.9% of AD infants' allergic manifestations. In addition to single-symptom allergic diseases, this study also identified several combinations of atopic symptoms. Conclusions: The proportion of multi-symptom allergies increased while single-symptom forms decreased. The observed temporal trends of allergic symptoms correspond to the atopic march.
ER -
VRBOVÁ, Markéta, Petra DOROCIAKOVÁ, Roman VYŠKOVSKÝ, Lubica MURINOVA PALKOVICOVA, Peter ČIŽNÁR, Katarina RAUSOVA, Scott J. N. MCNABB, Eva REICHRTOVA, Eva BUDINSKÁ and Vojtěch THON. Dynamics of allergy development during the first 5 years of life. \textit{European journal of pediatrics}. New York: Springer, 2018, vol.~177, No~9, p.~1317-1325. ISSN~0340-6199. Available from: https://dx.doi.org/10.1007/s00431-018-3188-9.
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