HOUSER, Josef, Lenka MALINOVSKÁ, Eva FUJDIAROVÁ, Gita JANČAŘÍKOVÁ, Jan KOMÁREK, Jitka HOLKOVÁ and Michaela WIMMEROVÁ. Structure-functional study of lectins: key players in a fight between host and pathogen. In Molecular Biophysics: ABC of the puzzle of Life. 2019.
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Basic information
Original name Structure-functional study of lectins: key players in a fight between host and pathogen
Authors HOUSER, Josef (203 Czech Republic, belonging to the institution), Lenka MALINOVSKÁ (203 Czech Republic, belonging to the institution), Eva FUJDIAROVÁ (203 Czech Republic, belonging to the institution), Gita JANČAŘÍKOVÁ (203 Czech Republic, belonging to the institution), Jan KOMÁREK (203 Czech Republic, belonging to the institution), Jitka HOLKOVÁ (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Molecular Biophysics: ABC of the puzzle of Life, 2019.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10600 1.6 Biological sciences
Country of publisher Croatia
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14740/19:00109356
Organization unit Central European Institute of Technology
Keywords in English lectins; pathogens; structure; protein function
Tags rivok
Tags International impact
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 11/3/2020 18:08.
Abstract
Lectins are proteins that reversibly interact with sugars. They role range from glycoprotein folding, through cell maturation to host-pathogen recognition. To describe a lectin we apply a broad range of biophysical techniques. In addition to analysis of its affinity and specificity, we also determine lectin structures and combine our findings with in silico modelling. Our results may find application in basic research, medicine as well as biotechnologies.
Links
EF16_013/0001776, research and development projectName: Česká infrastruktura pro integrativní strukturní biologii pro lidské zdraví
LM2015043, research and development projectName: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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