| LO PORTO, C., C. PALUMBO, J. BUXADERA-PALOMERO, C. CANAL, Petr JELÍNEK, Lenka ZAJÍČKOVÁ a P. FAVIA. On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications. Plasma processes and polymers. Weinheim: Wiley-VCH, 2018, roč. 15, č. 5, s. 1700232-1700242. ISSN 1612-8850. Dostupné z: https://dx.doi.org/10.1002/ppap.201700232. |
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@article{1512858,
author = {Lo Porto, C. and Palumbo, C. and BuxaderaandPalomero, J. and Canal, C. and Jelínek, Petr and Zajíčková, Lenka and Favia, P.},
article_location = {Weinheim},
article_number = {5},
doi = {http://dx.doi.org/10.1002/ppap.201700232},
keywords = {nanotexturing; plasma chemistry; plasma deposition; plasma treatment},
language = {eng},
issn = {1612-8850},
journal = {Plasma processes and polymers},
title = {On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications},
volume = {15},
year = {2018}
}
TY - JOUR
ID - 1512858
AU - Lo Porto, C. - Palumbo, C. - Buxadera-Palomero, J. - Canal, C. - Jelínek, Petr - Zajíčková, Lenka - Favia, P.
PY - 2018
TI - On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications
JF - Plasma processes and polymers
VL - 15
IS - 5
SP - 1700232
EP - 1700232
PB - Wiley-VCH
SN - 16128850
KW - nanotexturing
KW - plasma chemistry
KW - plasma deposition
KW - plasma treatment
N2 - Aerosol-assisted atmospheric pressure plasma allows for a one-step synthesis of vancomycin-containing nano-capsules. Morphological and chemical analyses are carried out to estimate how different discharge parameters affect the plasma deposition process. Nano-capsules size and abundance largely depend on the shell precursor content in the gas feed and on the drug concentration in the aerosol solution. Based on these results a deposition mechanism is proposed, where, interestingly, the key step is the formation of the nano-capsules in the plasma phase. Furthermore, the related antibacterial activity is proved against Staphylococcus aureus. Preliminary release tests indicate the possible exploitation of the plasma-deposited vancomycin-containing nano-capsules in the drug delivery field, and systems based on other bioactive molecules can be expected. [GRAPHICS] .
ER -
LO PORTO, C., C. PALUMBO, J. BUXADERA-PALOMERO, C. CANAL, Petr JELÍNEK, Lenka ZAJÍČKOVÁ a P. FAVIA. On the plasma deposition of vancomycin-containing nano-capsules for drug-delivery applications. \textit{Plasma processes and polymers}. Weinheim: Wiley-VCH, 2018, roč.~15, č.~5, s.~1700232-1700242. ISSN~1612-8850. Dostupné z: https://dx.doi.org/10.1002/ppap.201700232.
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