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@article{1522136, author = {Horáková, Magda and Horák, Tomáš and Parmová, Olesja and Bednařík, Josef and Voháňka, Stanislav}, article_location = {HOBOKEN}, article_number = {4}, doi = {http://dx.doi.org/10.1002/mus.26401}, keywords = {muscle relaxation; muscle strength dynamometer; myotonia; myotonic dystrophy; outcome measure; warm-up}, language = {eng}, issn = {0148-639X}, journal = {MUSCLE & NERVE}, title = {Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2}, url = {http://dx.doi.org/10.1002/mus.26401}, volume = {59}, year = {2019} }
TY - JOUR ID - 1522136 AU - Horáková, Magda - Horák, Tomáš - Parmová, Olesja - Bednařík, Josef - Voháňka, Stanislav PY - 2019 TI - Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2 JF - MUSCLE & NERVE VL - 59 IS - 4 SP - 431-435 EP - 431-435 PB - WILEY SN - 0148639X KW - muscle relaxation KW - muscle strength dynamometer KW - myotonia KW - myotonic dystrophy KW - outcome measure KW - warm-up UR - http://dx.doi.org/10.1002/mus.26401 L2 - http://dx.doi.org/10.1002/mus.26401 N2 - Introduction: The objective of this study was to develop a simple method for quantitative assessment of myotonia in patients with myotonic dystrophy type 1 (DM1) and DM2, to compare the myotonia severity, and to correlate this objective outcome with a subjective scale, the Myotonia Behaviour Scale (MBS). Methods: A commercially available dynamometer was used for all measurements. The relaxation time after voluntary contraction was measured in 20 patients with DM1, 25 patients with DM2, and 35 healthy controls. Results: The average relaxation time was 0.17 s in controls, 2.96 s in patients with DM1, and 0.4 s in patients with DM2. The correlation between relaxation time and MBS score was significant, 0.627 in patients with DM1 and 0.581 in patients with DM2. Discussion: Our method provides a valid and reliable quantitative measure of grip myotonia suitable as an outcome measure in clinical trials and as part of routine examinations to gather data on the natural history of myotonic disorders. Muscle Nerve 59:431-435, 2019 ER -
HORÁKOVÁ, Magda, Tomáš HORÁK, Olesja PARMOVÁ, Josef BEDNAŘÍK and Stanislav VOHÁŇKA. Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2. \textit{MUSCLE \&{}amp; NERVE}. HOBOKEN: WILEY, 2019, vol.~59, No~4, p.~431-435. ISSN~0148-639X. Available from: https://dx.doi.org/10.1002/mus.26401.
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