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@article{1522136,
author = {Horáková, Magda and Horák, Tomáš and Parmová, Olesja and Bednařík, Josef and Voháňka, Stanislav},
article_location = {HOBOKEN},
article_number = {4},
doi = {http://dx.doi.org/10.1002/mus.26401},
keywords = {muscle relaxation; muscle strength dynamometer; myotonia; myotonic dystrophy; outcome measure; warm-up},
language = {eng},
issn = {0148-639X},
journal = {MUSCLE & NERVE},
title = {Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2},
url = {http://dx.doi.org/10.1002/mus.26401},
volume = {59},
year = {2019}
}
TY - JOUR
ID - 1522136
AU - Horáková, Magda - Horák, Tomáš - Parmová, Olesja - Bednařík, Josef - Voháňka, Stanislav
PY - 2019
TI - Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2
JF - MUSCLE & NERVE
VL - 59
IS - 4
SP - 431-435
EP - 431-435
PB - WILEY
SN - 0148639X
KW - muscle relaxation
KW - muscle strength dynamometer
KW - myotonia
KW - myotonic dystrophy
KW - outcome measure
KW - warm-up
UR - http://dx.doi.org/10.1002/mus.26401
L2 - http://dx.doi.org/10.1002/mus.26401
N2 - Introduction: The objective of this study was to develop a simple method for quantitative assessment of myotonia in patients with myotonic dystrophy type 1 (DM1) and DM2, to compare the myotonia severity, and to correlate this objective outcome with a subjective scale, the Myotonia Behaviour Scale (MBS). Methods: A commercially available dynamometer was used for all measurements. The relaxation time after voluntary contraction was measured in 20 patients with DM1, 25 patients with DM2, and 35 healthy controls. Results: The average relaxation time was 0.17 s in controls, 2.96 s in patients with DM1, and 0.4 s in patients with DM2. The correlation between relaxation time and MBS score was significant, 0.627 in patients with DM1 and 0.581 in patients with DM2. Discussion: Our method provides a valid and reliable quantitative measure of grip myotonia suitable as an outcome measure in clinical trials and as part of routine examinations to gather data on the natural history of myotonic disorders. Muscle Nerve 59:431-435, 2019
ER -
HORÁKOVÁ, Magda, Tomáš HORÁK, Olesja PARMOVÁ, Josef BEDNAŘÍK and Stanislav VOHÁŇKA. Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2. \textit{MUSCLE \&{}amp; NERVE}. HOBOKEN: WILEY, 2019, vol.~59, No~4, p.~431-435. ISSN~0148-639X. Available from: https://dx.doi.org/10.1002/mus.26401.
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