Transbronchial biopsy from the upper pulmonary lobes is
associated with increased risk of pneumothorax - a
retrospective study

J 2019

Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study

HEROUT, Vladimír, Michaela HEROUTOVÁ, Zdeněk MERTA, Ivan ČUNDRLE, Kristián BRAT et. al.

Basic information

Original name

Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study

Authors

HEROUT, Vladimír (203 Czech Republic, belonging to the institution), Michaela HEROUTOVÁ (203 Czech Republic, belonging to the institution), Zdeněk MERTA (203 Czech Republic, belonging to the institution), Ivan ČUNDRLE (203 Czech Republic, belonging to the institution) and Kristián BRAT (703 Slovakia, guarantor, belonging to the institution)

Edition

BMC Pulmonary Medicine, London, Biomed Central LTD, 2019, 1471-2466

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30203 Respiratory systems

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.813

RIV identification code

RIV/00216224:14110/19:00109482

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1186/s12890-019-0820-z

UT WoS

000460042200001

Keywords in English

Pneumothorax; Bronchoscopy; Transbronchial biopsy; Upper pulmonary lobe; Pleural pressure

Abstract

V originále

BackgroundPneumothorax (PTX) is one of the most common complications of transbronchial biopsy (TBB). Previous research suggests that upper pulmonary lobe TBB may be associated with increased risk of PTX development. The aim of this study was to compare the risk of PTX after TBB performed from different pulmonary lobes.MethodsAll bronchoscopic records from the period January 1st, 2015 - December 31st, 2017 (from the Department of Respiratory Diseases, University Hospital Brno, Czech Republic) were retrospectively analyzed. Of the 3542 bronchoscopic records, 796 patients underwent TBB and were further analyzed. Basic demographic data, TBB procedure-related factors, smoking history and radiological features were analyzed. Furthermore, in patients who developed PTX, PTX onset, PTX symptoms, distribution of the abnormal radiological findings and duration of hospitalization were also analyzed.ResultsPatients who developed PTX had significantly lower body mass index (BMI) and more than 4 samples taken during procedure (all p<0.05). TBB performed from the left upper pulmonary lobe was associated with a significant risk of PTX development (OR 2.27; 95% CI 1.18-4.35; p=0.02). On the contrary, TBB performed from the right lower lobe was associated with a significant reduction of risk of developing PTX (OR 0.47; 95% CI 0.22-0.98; p=0.04). Logistic regression analysis showed BMI (OR 1.08; 95% CI 1.02-1.16; p=0.01), left upper lobe as sampling site (OR 2.15; 95% CI 1.13-4.11; p=0.02) and more than 4 samples taken (OR 1.91; 95% CI 1.04-3.49; p=0.04) to be significantly associated with PTX development.ConclusionsWe conclude that TBB from the left upper pulmonary lobe is associated with significantly increased risk of post-procedural PTX. The right lower pulmonary lobe seems to be the safest sampling site to perform TBB. In patients with diffuse-type pulmonary disease, TBB should be performed preferably from the right lower lobe in order to decrease the risk of post-procedural PTX.

Citovat

HEROUT, Vladimír, Michaela HEROUTOVÁ, Zdeněk MERTA, Ivan ČUNDRLE and Kristián BRAT. Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study. BMC Pulmonary Medicine. London: Biomed Central LTD, 2019, vol. 19, No 56, p. 1-6. ISSN 1471-2466. Available from: https://dx.doi.org/10.1186/s12890-019-0820-z.

@article{1522336,
   author = {Herout, Vladimír and Heroutová, Michaela and Merta, Zdeněk and Čundrle, Ivan and Brat, Kristián},
   article_location = {London},
   article_number = {56},
   doi = {http://dx.doi.org/10.1186/s12890-019-0820-z},
   keywords = {Pneumothorax; Bronchoscopy; Transbronchial biopsy; Upper pulmonary lobe; Pleural pressure},
   language = {eng},
   issn = {1471-2466},
   journal = {BMC Pulmonary Medicine},
   title = {Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study},
   url = {http://dx.doi.org/10.1186/s12890-019-0820-z},
   volume = {19},
   year = {2019}
}

TY  - JOUR
ID  - 1522336
AU  - Herout, Vladimír - Heroutová, Michaela - Merta, Zdeněk - Čundrle, Ivan - Brat, Kristián
PY  - 2019
TI  - Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study
JF  - BMC Pulmonary Medicine
VL  - 19
IS  - 56
SP  - 1-6
EP  - 1-6
PB  - Biomed Central LTD
SN  - 14712466
KW  - Pneumothorax
KW  - Bronchoscopy
KW  - Transbronchial biopsy
KW  - Upper pulmonary lobe
KW  - Pleural pressure
UR  - http://dx.doi.org/10.1186/s12890-019-0820-z
L2  - http://dx.doi.org/10.1186/s12890-019-0820-z
N2  - BackgroundPneumothorax (PTX) is one of the most common complications of transbronchial biopsy (TBB). Previous research suggests that upper pulmonary lobe TBB may be associated with increased risk of PTX development. The aim of this study was to compare the risk of PTX after TBB performed from different pulmonary lobes.MethodsAll bronchoscopic records from the period January 1st, 2015 - December 31st, 2017 (from the Department of Respiratory Diseases, University Hospital Brno, Czech Republic) were retrospectively analyzed. Of the 3542 bronchoscopic records, 796 patients underwent TBB and were further analyzed. Basic demographic data, TBB procedure-related factors, smoking history and radiological features were analyzed. Furthermore, in patients who developed PTX, PTX onset, PTX symptoms, distribution of the abnormal radiological findings and duration of hospitalization were also analyzed.ResultsPatients who developed PTX had significantly lower body mass index (BMI) and more than 4 samples taken during procedure (all p<0.05). TBB performed from the left upper pulmonary lobe was associated with a significant risk of PTX development (OR 2.27; 95% CI 1.18-4.35; p=0.02). On the contrary, TBB performed from the right lower lobe was associated with a significant reduction of risk of developing PTX (OR 0.47; 95% CI 0.22-0.98; p=0.04). Logistic regression analysis showed BMI (OR 1.08; 95% CI 1.02-1.16; p=0.01), left upper lobe as sampling site (OR 2.15; 95% CI 1.13-4.11; p=0.02) and more than 4 samples taken (OR 1.91; 95% CI 1.04-3.49; p=0.04) to be significantly associated with PTX development.ConclusionsWe conclude that TBB from the left upper pulmonary lobe is associated with significantly increased risk of post-procedural PTX. The right lower pulmonary lobe seems to be the safest sampling site to perform TBB. In patients with diffuse-type pulmonary disease, TBB should be performed preferably from the right lower lobe in order to decrease the risk of post-procedural PTX.
ER  -

HEROUT, Vladimír, Michaela HEROUTOVÁ, Zdeněk MERTA, Ivan ČUNDRLE and Kristián BRAT. Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study. \textit{BMC Pulmonary Medicine}. London: Biomed Central LTD, 2019, vol.~19, No~56, p.~1-6. ISSN~1471-2466. Available from: https://dx.doi.org/10.1186/s12890-019-0820-z.

Detailed Information on Publication Record