a 2019

Multiple neuroendocrine tumor of the small bowel diagnosed by capsule endoscopy

KUNOVSKÝ, Lumír; Milan DASTYCH; Radek KROUPA; Jiří DOLINA; Petr KYSELA et. al.

Základní údaje

Originální název

Multiple neuroendocrine tumor of the small bowel diagnosed by capsule endoscopy

Autoři

KUNOVSKÝ, Lumír (203 Česká republika, garant, domácí); Milan DASTYCH (203 Česká republika, domácí); Radek KROUPA (203 Česká republika, domácí); Jiří DOLINA (203 Česká republika, domácí); Petr KYSELA (203 Česká republika, domácí); Roman SVATOŇ (703 Slovensko, domácí); Zdeněk KALA (203 Česká republika, domácí); Jakub VLAŽNÝ (203 Česká republika, domácí); Jakub HUSTÝ (203 Česká republika, domácí); Michal EID (203 Česká republika, domácí); Jan TRNA (203 Česká republika, domácí) a Karolina POREDSKÁ (203 Česká republika, domácí)

Vydání

ESGE Days 2019, Prague, 2019

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30219 Gastroenterology and hepatology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Kód RIV

RIV/00216224:14110/19:00109531

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

neuroendocrine tumor; obscure gastrointestinal bleeding; capsule endoscopy; small bowel; surgery

Štítky

Příznaky

Mezinárodní význam
Změněno: 21. 4. 2020 10:12, Mgr. Tereza Miškechová

Anotace

V originále

Aims Primary malignant tumors of the small bowel constitute only about 1 – 2% of all gastrointestinal neoplasms. Although neuroendocrine tumors (NETs) are relatively rare, they still represent the second most common malignancy of the small bowel (after adenocarcinoma). Clinical manifestations include abdominal pain, bowel obstruction, diarrhea, weight loss and bleeding. The differential diagnosis of obscure gastrointestinal bleeding can sometimes be challenging for endoscopic as well as for radiological methods. The aim of the lecture is to present the diagnostic and therapeutic management of a patient with NET of the small bowel. Methods A literature research (in MEDLINE, PubMed and Google Scholar databases) was done focusing on diagnostics, endoscopic and surgical treatment of neuroendocrine tumor of the small bowel. Results We present a case of an 80-year-old man suffering from severe hypochromic anemia. Routine endoscopic methods did not show any any pathology explaining the severe anemia. Finally, a single ulcerative infiltration of the ileum was diagnosed by capsule endoscopy (CE). CT enterography did not reveal any other lesions. In accordance with a positive chromogranin A, endoscopic and radiological methods, a suspicion of NET was expressed. During the surgery 7 lesions were found and a resection of 120 cm of ileum was performed. The histology confirmed a diagnosis of NET grade 1, with a total number of 15 NET lesions in the specimen. Conclusions NETs located in the duodenum up to 1 cm in size can be treated endoscopically and are mostly isolated lesions. On the other hand, surgical treatment is recommended for NETs in the jejunoileum. They have a greater propensity to metastasize and NETs in this localization can even form more lesions. We present a patient with 15 NET lesions in the ileum diagnosed by CE and successfully treated by surgical resection of the ileum.