J 2019

Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset

GOMEZ-VILDA, Pedro, Zoltan GALAZ, Jiri MEKYSKA, Jose M. VICENTE, Andres GOMEZ-RODELLAR et. al.

Základní údaje

Originální název

Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset

Autoři

GOMEZ-VILDA, Pedro (724 Španělsko, garant), Zoltan GALAZ (203 Česká republika), Jiri MEKYSKA (203 Česká republika), Jose M. VICENTE (724 Španělsko), Andres GOMEZ-RODELLAR (724 Španělsko), Daniel PALACIOS-ALONSO (724 Španělsko), Zdenek SMEKAL (203 Česká republika), Ilona ELIÁŠOVÁ (203 Česká republika, domácí), Milena KOŠŤÁLOVÁ (203 Česká republika, domácí) a Irena REKTOROVÁ (203 Česká republika, domácí)

Vydání

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS, SINGAPORE, WORLD SCIENTIFIC PUBL CO PTE LTD, 2019, 0129-0657

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Singapur

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.604

Kód RIV

RIV/00216224:14740/19:00108466

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1142/S0129065718500375

UT WoS

000459454300003

Klíčová slova anglicky

Neurodegenerative disorder; Parkinson's Disease; speech neuromotor activity; aging voice; hypokinetic dysarthria

Štítky

14110127, 14110221, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 4. 3. 2020 13:45, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

Neurodegenerative pathologies as Parkinson's Disease (PD) show important distortions in speech, affecting fluency, prosody, articulation and phonation. Classically, measurements based on articulation gestures altering formant positions, as the Vocal Space Area (VSA) or the Formant Centralization Ratio (FCR) have been proposed to measure speech distortion, but these markers are based mainly on static positions of sustained vowels. The present study introduces a measurement based on the mutual information distance among probability density functions of kinematic correlates derived from formant dynamics. An absolute kinematic velocity associated to the position of the jaw and tongue articulation gestures is estimated and modeled statistically. The distribution of this feature may differentiate PD patients from normative speakers during sustained vowel emission. The study is based on a limited database of 53 male PD patients, contrasted to a very selected and stable set of eight normative speakers. In this sense, distances based on Kullback-Leibler divergence seem to be sensitive to PD articulation instability. Correlation studies show statistically relevant relationship between information contents based on articulation instability to certain motor and nonmotor clinical scores, such as freezing of gait, or sleep disorders. Remarkably, one of the statistically relevant correlations point out to the time interval passed since the first diagnostic. These results stress the need of defining scoring scales specifically designed for speech disability estimation and monitoring methodologies in degenerative diseases of neuromotor origin.

Návaznosti

NV16-30805A, projekt VaV
Název: Efekt neinvazivní stimulace mozku na hypokinetickou dysartrii, mikrografii a mozkovou plasticitu u pacientů s Parkinsonovou nemocí
Zobrazeno: 28. 10. 2024 16:05