Detailed Information on Publication Record
2019
Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset
GOMEZ-VILDA, Pedro, Zoltan GALAZ, Jiri MEKYSKA, Jose M. VICENTE, Andres GOMEZ-RODELLAR et. al.Basic information
Original name
Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset
Authors
GOMEZ-VILDA, Pedro (724 Spain, guarantor), Zoltan GALAZ (203 Czech Republic), Jiri MEKYSKA (203 Czech Republic), Jose M. VICENTE (724 Spain), Andres GOMEZ-RODELLAR (724 Spain), Daniel PALACIOS-ALONSO (724 Spain), Zdenek SMEKAL (203 Czech Republic), Ilona ELIÁŠOVÁ (203 Czech Republic, belonging to the institution), Milena KOŠŤÁLOVÁ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, belonging to the institution)
Edition
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS, SINGAPORE, WORLD SCIENTIFIC PUBL CO PTE LTD, 2019, 0129-0657
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30210 Clinical neurology
Country of publisher
Singapore
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 5.604
RIV identification code
RIV/00216224:14740/19:00108466
Organization unit
Central European Institute of Technology
UT WoS
000459454300003
Keywords in English
Neurodegenerative disorder; Parkinson's Disease; speech neuromotor activity; aging voice; hypokinetic dysarthria
Tags
International impact, Reviewed
Změněno: 4/3/2020 13:45, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
Neurodegenerative pathologies as Parkinson's Disease (PD) show important distortions in speech, affecting fluency, prosody, articulation and phonation. Classically, measurements based on articulation gestures altering formant positions, as the Vocal Space Area (VSA) or the Formant Centralization Ratio (FCR) have been proposed to measure speech distortion, but these markers are based mainly on static positions of sustained vowels. The present study introduces a measurement based on the mutual information distance among probability density functions of kinematic correlates derived from formant dynamics. An absolute kinematic velocity associated to the position of the jaw and tongue articulation gestures is estimated and modeled statistically. The distribution of this feature may differentiate PD patients from normative speakers during sustained vowel emission. The study is based on a limited database of 53 male PD patients, contrasted to a very selected and stable set of eight normative speakers. In this sense, distances based on Kullback-Leibler divergence seem to be sensitive to PD articulation instability. Correlation studies show statistically relevant relationship between information contents based on articulation instability to certain motor and nonmotor clinical scores, such as freezing of gait, or sleep disorders. Remarkably, one of the statistically relevant correlations point out to the time interval passed since the first diagnostic. These results stress the need of defining scoring scales specifically designed for speech disability estimation and monitoring methodologies in degenerative diseases of neuromotor origin.
Links
| NV16-30805A, research and development project |
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