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@article{1527162,
author = {GomezandVilda, Pedro and Galaz, Zoltan and Mekyska, Jiri and Vicente, Jose M. and GomezandRodellar, Andres and PalaciosandAlonso, Daniel and Smekal, Zdenek and Eliášová, Ilona and Košťálová, Milena and Rektorová, Irena},
article_location = {SINGAPORE},
article_number = {2},
doi = {http://dx.doi.org/10.1142/S0129065718500375},
keywords = {Neurodegenerative disorder; Parkinson's Disease; speech neuromotor activity; aging voice; hypokinetic dysarthria},
language = {eng},
issn = {0129-0657},
journal = {INTERNATIONAL JOURNAL OF NEURAL SYSTEMS},
title = {Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset},
url = {https://www.worldscientific.com/doi/pdf/10.1142/S0129065718500375},
volume = {29},
year = {2019}
}
TY - JOUR
ID - 1527162
AU - Gomez-Vilda, Pedro - Galaz, Zoltan - Mekyska, Jiri - Vicente, Jose M. - Gomez-Rodellar, Andres - Palacios-Alonso, Daniel - Smekal, Zdenek - Eliášová, Ilona - Košťálová, Milena - Rektorová, Irena
PY - 2019
TI - Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset
JF - INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
VL - 29
IS - 2
SP - 1-13
EP - 1-13
PB - WORLD SCIENTIFIC PUBL CO PTE LTD
SN - 01290657
KW - Neurodegenerative disorder
KW - Parkinson's Disease
KW - speech neuromotor activity
KW - aging voice
KW - hypokinetic dysarthria
UR - https://www.worldscientific.com/doi/pdf/10.1142/S0129065718500375
L2 - https://www.worldscientific.com/doi/pdf/10.1142/S0129065718500375
N2 - Neurodegenerative pathologies as Parkinson's Disease (PD) show important distortions in speech, affecting fluency, prosody, articulation and phonation. Classically, measurements based on articulation gestures altering formant positions, as the Vocal Space Area (VSA) or the Formant Centralization Ratio (FCR) have been proposed to measure speech distortion, but these markers are based mainly on static positions of sustained vowels. The present study introduces a measurement based on the mutual information distance among probability density functions of kinematic correlates derived from formant dynamics. An absolute kinematic velocity associated to the position of the jaw and tongue articulation gestures is estimated and modeled statistically. The distribution of this feature may differentiate PD patients from normative speakers during sustained vowel emission. The study is based on a limited database of 53 male PD patients, contrasted to a very selected and stable set of eight normative speakers. In this sense, distances based on Kullback-Leibler divergence seem to be sensitive to PD articulation instability. Correlation studies show statistically relevant relationship between information contents based on articulation instability to certain motor and nonmotor clinical scores, such as freezing of gait, or sleep disorders. Remarkably, one of the statistically relevant correlations point out to the time interval passed since the first diagnostic. These results stress the need of defining scoring scales specifically designed for speech disability estimation and monitoring methodologies in degenerative diseases of neuromotor origin.
ER -
GOMEZ-VILDA, Pedro, Zoltan GALAZ, Jiri MEKYSKA, Jose M. VICENTE, Andres GOMEZ-RODELLAR, Daniel PALACIOS-ALONSO, Zdenek SMEKAL, Ilona ELIÁŠOVÁ, Milena KOŠŤÁLOVÁ and Irena REKTOROVÁ. Vowel Articulation Dynamic Stability Related to Parkinson's Disease Rating Features: Male Dataset. \textit{INTERNATIONAL JOURNAL OF NEURAL SYSTEMS}. SINGAPORE: WORLD SCIENTIFIC PUBL CO PTE LTD, 2019, vol.~29, No~2, p.~1-13. ISSN~0129-0657. Available from: https://dx.doi.org/10.1142/S0129065718500375.
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