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@inbook{1530759,
author = {Midlik, Adam and Hutařová Vařeková, Ivana and Hutař, Jan and Moturu, Tarakaramji and Navrátilová, Veronika and Koča, Jaroslav and Berka, Karel and Svobodová Vařeková, Radka},
address = {New York},
booktitle = {Protein supersecondary structures: Methods and protocols},
doi = {http://dx.doi.org/10.1007/978-1-4939-9161-7_3},
edition = {Second Edition},
editor = {Alexander E. Kister},
keywords = {Annotation; Secondary structure; Secondary structure elements; Protein family; Protein domain; SecStrAnnotator; Structural alignment; Secondary structure assignment},
howpublished = {tištěná verze "print"},
language = {eng},
location = {New York},
isbn = {978-1-4939-9160-0},
pages = {47-71},
publisher = {Humana Press},
title = {Automated family-wide annotation of secondary structure elements},
url = {https://link.springer.com/protocol/10.1007/978-1-4939-9161-7_3},
year = {2019}
}
TY - CHAP
ID - 1530759
AU - Midlik, Adam - Hutařová Vařeková, Ivana - Hutař, Jan - Moturu, Tarakaramji - Navrátilová, Veronika - Koča, Jaroslav - Berka, Karel - Svobodová Vařeková, Radka
PY - 2019
TI - Automated family-wide annotation of secondary structure elements
VL - Methods in Molecular Biology
PB - Humana Press
CY - New York
SN - 9781493991600
KW - Annotation
KW - Secondary structure
KW - Secondary structure elements
KW - Protein family
KW - Protein domain
KW - SecStrAnnotator
KW - Structural alignment
KW - Secondary structure assignment
UR - https://link.springer.com/protocol/10.1007/978-1-4939-9161-7_3
L2 - https://link.springer.com/protocol/10.1007/978-1-4939-9161-7_3
N2 - Secondary structure elements (SSEs) are inherent parts of protein structures, and their arrangement is characteristic for each protein family. Therefore, annotation of SSEs can facilitate orientation in the vast number of homologous structures which is now available for many protein families. It also provides a way to identify and annotate the key regions, like active sites and channels, and subsequently answer the key research questions, such as understanding of molecular function and its variability. This chapter introduces the concept of SSE annotation and describes the workflow for obtaining SSE annotation for the members of a selected protein family using program SecStrAnnotator.
ER -
MIDLIK, Adam, Ivana HUTAŘOVÁ VAŘEKOVÁ, Jan HUTAŘ, Tarakaramji MOTURU, Veronika NAVRÁTILOVÁ, Jaroslav KOČA, Karel BERKA and Radka SVOBODOVÁ VAŘEKOVÁ. Automated family-wide annotation of secondary structure elements. In Alexander E. Kister. \textit{Protein supersecondary structures: Methods and protocols}. Second Edition. New York: Humana Press, 2019, p.~47-71. Methods in Molecular Biology. ISBN~978-1-4939-9160-0. Available from: https://dx.doi.org/10.1007/978-1-4939-9161-7\_{}3.
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