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@inbook{1530759, author = {Midlik, Adam and Hutařová Vařeková, Ivana and Hutař, Jan and Moturu, Tarakaramji and Navrátilová, Veronika and Koča, Jaroslav and Berka, Karel and Svobodová Vařeková, Radka}, address = {New York}, booktitle = {Protein supersecondary structures: Methods and protocols}, doi = {http://dx.doi.org/10.1007/978-1-4939-9161-7_3}, edition = {Second Edition}, editor = {Alexander E. Kister}, keywords = {Annotation; Secondary structure; Secondary structure elements; Protein family; Protein domain; SecStrAnnotator; Structural alignment; Secondary structure assignment}, howpublished = {tištěná verze "print"}, language = {eng}, location = {New York}, isbn = {978-1-4939-9160-0}, pages = {47-71}, publisher = {Humana Press}, title = {Automated family-wide annotation of secondary structure elements}, url = {https://link.springer.com/protocol/10.1007/978-1-4939-9161-7_3}, year = {2019} }
TY - CHAP ID - 1530759 AU - Midlik, Adam - Hutařová Vařeková, Ivana - Hutař, Jan - Moturu, Tarakaramji - Navrátilová, Veronika - Koča, Jaroslav - Berka, Karel - Svobodová Vařeková, Radka PY - 2019 TI - Automated family-wide annotation of secondary structure elements VL - Methods in Molecular Biology PB - Humana Press CY - New York SN - 9781493991600 KW - Annotation KW - Secondary structure KW - Secondary structure elements KW - Protein family KW - Protein domain KW - SecStrAnnotator KW - Structural alignment KW - Secondary structure assignment UR - https://link.springer.com/protocol/10.1007/978-1-4939-9161-7_3 L2 - https://link.springer.com/protocol/10.1007/978-1-4939-9161-7_3 N2 - Secondary structure elements (SSEs) are inherent parts of protein structures, and their arrangement is characteristic for each protein family. Therefore, annotation of SSEs can facilitate orientation in the vast number of homologous structures which is now available for many protein families. It also provides a way to identify and annotate the key regions, like active sites and channels, and subsequently answer the key research questions, such as understanding of molecular function and its variability. This chapter introduces the concept of SSE annotation and describes the workflow for obtaining SSE annotation for the members of a selected protein family using program SecStrAnnotator. ER -
MIDLIK, Adam, Ivana HUTAŘOVÁ VAŘEKOVÁ, Jan HUTAŘ, Tarakaramji MOTURU, Veronika NAVRÁTILOVÁ, Jaroslav KOČA, Karel BERKA and Radka SVOBODOVÁ VAŘEKOVÁ. Automated family-wide annotation of secondary structure elements. In Alexander E. Kister. \textit{Protein supersecondary structures: Methods and protocols}. Second Edition. New York: Humana Press, 2019, p.~47-71. Methods in Molecular Biology. ISBN~978-1-4939-9160-0. Available from: https://dx.doi.org/10.1007/978-1-4939-9161-7\_{}3.
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