Detailed Information on Publication Record
2019
Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?
VAGASKÁ, Eva, Alexandra LITAVCOVÁ, Iva ŠROTOVÁ, Eva VLČKOVÁ, Miloš KEŘKOVSKÝ et. al.Basic information
Original name
Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?
Authors
VAGASKÁ, Eva (703 Slovakia, belonging to the institution), Alexandra LITAVCOVÁ (703 Slovakia, belonging to the institution), Iva ŠROTOVÁ (203 Czech Republic, belonging to the institution), Eva VLČKOVÁ (203 Czech Republic, belonging to the institution), Miloš KEŘKOVSKÝ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution) and Blanka ADAMOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Medicine, Philadelphia, Lippincott Williams & Wilkins, 2019, 0025-7974
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30210 Clinical neurology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 1.552
RIV identification code
RIV/00216224:14110/19:00109783
Organization unit
Faculty of Medicine
UT WoS
000467337400079
Keywords in English
DN4; low back pain; magnetic resonance imaging; neuropathic pain
Tags
International impact, Reviewed
Změněno: 31/3/2020 22:20, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP -female sex (odds ratio [OR]=11.9) and a mean pain intensity of >= 4.5 in the previous 4 weeks (OR=13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP.
Links
| MUNI/A/1072/2017, interní kód MU |
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| MUNI/A/1419/2018, interní kód MU |
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| ROZV/24/LF/2018, interní kód MU |
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