Detailed Information on Publication Record
2019
Isoflavones
KŘÍŽOVÁ, Ludmila, Kateřina DADÁKOVÁ, Jitka KAŠPAROVSKÁ and Tomáš KAŠPAROVSKÝBasic information
Original name
Isoflavones
Authors
KŘÍŽOVÁ, Ludmila (203 Czech Republic, belonging to the institution), Kateřina DADÁKOVÁ (203 Czech Republic, belonging to the institution), Jitka KAŠPAROVSKÁ (203 Czech Republic, belonging to the institution) and Tomáš KAŠPAROVSKÝ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Molecules, BASEL, Mayer und Muller, 2019, 1420-3049
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10608 Biochemistry and molecular biology
Country of publisher
Switzerland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.267
RIV identification code
RIV/00216224:14310/19:00109919
Organization unit
Faculty of Science
UT WoS
000465503800052
Keywords in English
isoflavones; phytoestrogens; daidzein; genistein; glycitein; formononetin; biochanin A; equol
Tags
Tags
International impact, Reviewed
Změněno: 26/6/2020 15:58, Mgr. Kateřina Dadáková, Ph.D.
Abstract
V originále
Phytoestrogens are naturally occurring nonsteroidal phenolic plant compounds that, due to their molecular structure and size, resemble vertebrate steroids estrogens. This review is focused on plant flavonoids isoflavones, which are ranked among the most estrogenic compounds. The main dietary sources of isoflavones for humans are soybean and soybean products, which contain mainly daidzein and genistein. When they are consumed, they exert estrogenic and/or antiestrogenic effects. Isoflavones are considered chemoprotective and can be used as an alternative therapy for a wide range of hormonal disorders, including several cancer types, namely breast cancer and prostate cancer, cardiovascular diseases, osteoporosis, or menopausal symptoms. On the other hand, isoflavones may also be considered endocrine disruptors with possible negative influences on the state of health in a certain part of the population or on the environment. This review deals with isoflavone classification, structure, and occurrence, with their metabolism, biological, and health effects in humans and animals, and with their utilization and potential risks.
Links
| MUNI/A/1100/2017, interní kód MU |
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