Epidemiological analyses to inform stroke clinical practice guidelines development

LÍČENÍK, Radim, Jitka KLUGAROVÁ, Andrea POKORNÁ, Monika BEZDĚKOVÁ, Jiří JARKOVSKÝ, Petra BÚŘILOVÁ, Tomáš NEČAS, Jan MUŽÍK, Silvie ŠEBESTOVÁ, Dana DOLANOVÁ, Martin HUNČOVSKÝ, Ladislav DUŠEK and Miloslav KLUGAR. Epidemiological analyses to inform stroke clinical practice guidelines development. International Journal of Evidence-Based Healthcare. Wolters Kluwer/Lippincott Williams & Wilkins, 2019, vol. 17, Supplement 1, p. „S53“-„S56“, 4 pp. ISSN 1744-1609. Available from: https://dx.doi.org/10.1097/XEB.0000000000000189.

Basic information

• Original name: Epidemiological analyses to inform stroke clinical practice guidelines development
• Authors: LÍČENÍK, Radim (203 Czech Republic, belonging to the institution), Jitka KLUGAROVÁ (203 Czech Republic, belonging to the institution), Andrea POKORNÁ (203 Czech Republic, guarantor, belonging to the institution), Monika BEZDĚKOVÁ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Petra BÚŘILOVÁ (203 Czech Republic, belonging to the institution), Tomáš NEČAS (203 Czech Republic), Jan MUŽÍK (203 Czech Republic, belonging to the institution), Silvie ŠEBESTOVÁ (203 Czech Republic), Dana DOLANOVÁ (703 Slovakia, belonging to the institution), Martin HUNČOVSKÝ (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution) and Miloslav KLUGAR (203 Czech Republic, belonging to the institution).
• Edition: International Journal of Evidence-Based Healthcare, Wolters Kluwer/Lippincott Williams & Wilkins, 2019, 1744-1609.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30230 Other clinical medicine subjects
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 1.930
• RIV identification code: RIV/00216224:14110/19:00110132
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1097/XEB.0000000000000189
• UT WoS: 000511111600017
• Keywords in English: aortic valve disease; atrial fibrillation; atrial septal defect; clinical practice guidelines; endocarditis; flutter; intravenous thrombolysis; ischaemic stroke; mechanical thrombectomy; secondary prevention
• Tags: 14110611, 14119612, 14119613, rivok
• Tags: International impact, Reviewed

Abstract

Stroke is one of the leading causes of mortality and the leading cause of functional impairment and cognitive deficits worldwide. It is important that clinical practice guidelines development is based on robust statistical and epidemiological data and their analysis throughout the whole process of guidelines development and implementation. The aim of this short communication is to analyse epidemiology of prevalence and incidence of ischaemic stroke, its main causes, brain imaging using MRI, recanalization therapies, secondary prevention with antiplatelet and anticoagulants, mortality data and to inform development of stroke clinical practice guidelines in the Czech Republic. The main analysed diagnosis was I63 (cerebral infarction) and secondary diagnoses were: I48 (atrial fibrillation and flutter), I35.9 (nonspecified aortic valve disease), Q21.1 (atrial septal defect) or I33.0 (acute and subacute endocarditis). We have also analysed use of brain imaging with MRI, recanalization treatment using intravenous thrombolysis and mechanical thrombectomy, stroke secondary prevention with antiplatelet drugs and anticoagulation as well as hospital admissions and mortality. In total, 159 344 patients were diagnosed with an ischaemic stroke from 2015 to 2017. Average prevalence of ischaemic stroke in the Czech Republic is 54.9 patients per 100 000. 22.2% of patients with stroke received intravenous thrombolysis or mechanical thrombectomy in 2017.