The prognostic value of ultra low-dose thallium myocardial
perfusion protocol using CZT SPECT

J 2019

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

BEDNÁROVÁ, Veronika; Vladimír KINCL; Milan KAMÍNEK; Jiří VAŠINA; Roman PANOVSKÝ et. al.

Basic information

Original name

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

Authors

BEDNÁROVÁ, Veronika (703 Slovakia, belonging to the institution); Vladimír KINCL (203 Czech Republic, guarantor, belonging to the institution); Milan KAMÍNEK (203 Czech Republic); Jiří VAŠINA (203 Czech Republic); Roman PANOVSKÝ (203 Czech Republic, belonging to the institution) and Jan MÁCHAL (203 Czech Republic, belonging to the institution)

Edition

International Journal of Cardiovascular Imaging, Dordrecht, Springer, 2019, 1569-5794

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Netherlands

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Impact factor

Impact factor: 1.969

RIV identification code

RIV/00216224:14110/19:00110178

Organization unit

Faculty of Medicine

DOI

https://doi.org/10.1007/s10554-019-01535-7

UT WoS

000469003200022

EID Scopus

2-s2.0-85060573190

Keywords in English

Myocardial perfusion; Thallium; Low-dose; CZT; SPECT; Prognostic value

Abstract

In the original language

The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5MBq (0.014mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p<0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.

Cite

BEDNÁROVÁ, Veronika; Vladimír KINCL; Milan KAMÍNEK; Jiří VAŠINA; Roman PANOVSKÝ and Jan MÁCHAL. The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT. International Journal of Cardiovascular Imaging. Dordrecht: Springer, 2019, vol. 35, No 6, p. 1163-1167. ISSN 1569-5794. Available from: https://doi.org/10.1007/s10554-019-01535-7.

@article{1545811,
   author = {Bednárová, Veronika and Kincl, Vladimír and Kamínek, Milan and Vašina, Jiří and Panovský, Roman and Máchal, Jan},
   article_location = {Dordrecht},
   article_number = {6},
   doi = {https://doi.org/10.1007/s10554-019-01535-7},
   keywords = {Myocardial perfusion; Thallium; Low-dose; CZT; SPECT; Prognostic value},
   language = {eng},
   issn = {1569-5794},
   journal = {International Journal of Cardiovascular Imaging},
   title = {The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT},
   url = {http://dx.doi.org/10.1007/s10554-019-01535-7},
   volume = {35},
   year = {2019}
}

TY  - JOUR
ID  - 1545811
AU  - Bednárová, Veronika - Kincl, Vladimír - Kamínek, Milan - Vašina, Jiří - Panovský, Roman - Máchal, Jan
PY  - 2019
TI  - The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT
JF  - International Journal of Cardiovascular Imaging
VL  - 35
IS  - 6
SP  - 1163-1167
EP  - 1163-1167
PB  - Springer
SN  - 15695794
KW  - Myocardial perfusion
KW  - Thallium
KW  - Low-dose
KW  - CZT
KW  - SPECT
KW  - Prognostic value
UR  - http://dx.doi.org/10.1007/s10554-019-01535-7
L2  - http://dx.doi.org/10.1007/s10554-019-01535-7
N2  - The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5MBq (0.014mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p<0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.
ER  -

BEDNÁROVÁ, Veronika; Vladimír KINCL; Milan KAMÍNEK; Jiří VAŠINA; Roman PANOVSKÝ and Jan MÁCHAL. The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT. \textit{International Journal of Cardiovascular Imaging}. Dordrecht: Springer, 2019, vol.~35, No~6, p.~1163-1167. ISSN~1569-5794. Available from: https://doi.org/10.1007/s10554-019-01535-7.

Přehled o publikaci