The prognostic value of ultra low-dose thallium myocardial
perfusion protocol using CZT SPECT

J 2019

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

BEDNÁROVÁ, Veronika, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Roman PANOVSKÝ et. al.

Basic information

Original name

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

Authors

BEDNÁROVÁ, Veronika (703 Slovakia, belonging to the institution), Vladimír KINCL (203 Czech Republic, guarantor, belonging to the institution), Milan KAMÍNEK (203 Czech Republic), Jiří VAŠINA (203 Czech Republic), Roman PANOVSKÝ (203 Czech Republic, belonging to the institution) and Jan MÁCHAL (203 Czech Republic, belonging to the institution)

Edition

International Journal of Cardiovascular Imaging, Dordrecht, Springer, 2019, 1569-5794

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.969

RIV identification code

RIV/00216224:14110/19:00110178

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s10554-019-01535-7

UT WoS

000469003200022

Keywords in English

Myocardial perfusion; Thallium; Low-dose; CZT; SPECT; Prognostic value

Abstract

V originále

The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5MBq (0.014mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p<0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.

Citovat

BEDNÁROVÁ, Veronika, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Roman PANOVSKÝ and Jan MÁCHAL. The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT. International Journal of Cardiovascular Imaging. Dordrecht: Springer, 2019, vol. 35, No 6, p. 1163-1167. ISSN 1569-5794. Available from: https://dx.doi.org/10.1007/s10554-019-01535-7.

@article{1545811,
   author = {Bednárová, Veronika and Kincl, Vladimír and Kamínek, Milan and Vašina, Jiří and Panovský, Roman and Máchal, Jan},
   article_location = {Dordrecht},
   article_number = {6},
   doi = {http://dx.doi.org/10.1007/s10554-019-01535-7},
   keywords = {Myocardial perfusion; Thallium; Low-dose; CZT; SPECT; Prognostic value},
   language = {eng},
   issn = {1569-5794},
   journal = {International Journal of Cardiovascular Imaging},
   title = {The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT},
   url = {http://dx.doi.org/10.1007/s10554-019-01535-7},
   volume = {35},
   year = {2019}
}

TY  - JOUR
ID  - 1545811
AU  - Bednárová, Veronika - Kincl, Vladimír - Kamínek, Milan - Vašina, Jiří - Panovský, Roman - Máchal, Jan
PY  - 2019
TI  - The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT
JF  - International Journal of Cardiovascular Imaging
VL  - 35
IS  - 6
SP  - 1163-1167
EP  - 1163-1167
PB  - Springer
SN  - 15695794
KW  - Myocardial perfusion
KW  - Thallium
KW  - Low-dose
KW  - CZT
KW  - SPECT
KW  - Prognostic value
UR  - http://dx.doi.org/10.1007/s10554-019-01535-7
L2  - http://dx.doi.org/10.1007/s10554-019-01535-7
N2  - The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5MBq (0.014mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p<0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.
ER  -

BEDNÁROVÁ, Veronika, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Roman PANOVSKÝ and Jan MÁCHAL. The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT. \textit{International Journal of Cardiovascular Imaging}. Dordrecht: Springer, 2019, vol.~35, No~6, p.~1163-1167. ISSN~1569-5794. Available from: https://dx.doi.org/10.1007/s10554-019-01535-7.

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