BEDNÁROVÁ, Veronika, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Roman PANOVSKÝ and Jan MÁCHAL. The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT. International Journal of Cardiovascular Imaging. Dordrecht: Springer, 2019, vol. 35, No 6, p. 1163-1167. ISSN 1569-5794. Available from: https://dx.doi.org/10.1007/s10554-019-01535-7.
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Basic information
Original name The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT
Authors BEDNÁROVÁ, Veronika (703 Slovakia, belonging to the institution), Vladimír KINCL (203 Czech Republic, guarantor, belonging to the institution), Milan KAMÍNEK (203 Czech Republic), Jiří VAŠINA (203 Czech Republic), Roman PANOVSKÝ (203 Czech Republic, belonging to the institution) and Jan MÁCHAL (203 Czech Republic, belonging to the institution).
Edition International Journal of Cardiovascular Imaging, Dordrecht, Springer, 2019, 1569-5794.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.969
RIV identification code RIV/00216224:14110/19:00110178
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s10554-019-01535-7
UT WoS 000469003200022
Keywords in English Myocardial perfusion; Thallium; Low-dose; CZT; SPECT; Prognostic value
Tags 14110115, 14110518, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 9/5/2022 13:19.
Abstract
The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5MBq (0.014mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p<0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.
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