Detailed Information on Publication Record
2019
Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy
ŘEHULKA, Pavel, Jan CIMBALNIK, Martin PAIL, Jan CHRASTINA, Markéta HERMANOVÁ et. al.Basic information
Original name
Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy
Authors
ŘEHULKA, Pavel (203 Czech Republic, guarantor, belonging to the institution), Jan CIMBALNIK (203 Czech Republic), Martin PAIL (203 Czech Republic, belonging to the institution), Jan CHRASTINA (203 Czech Republic, belonging to the institution), Markéta HERMANOVÁ (203 Czech Republic, belonging to the institution) and Milan BRÁZDIL (203 Czech Republic, belonging to the institution)
Edition
Clinical Neurophysiology, Clare, Elsevier Ireland, 2019, 1388-2457
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30210 Clinical neurology
Country of publisher
Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.214
RIV identification code
RIV/00216224:14110/19:00110199
Organization unit
Faculty of Medicine
UT WoS
000469338500008
Keywords in English
High frequency oscillations; Hippocampus; Hippocampal sclerosis; Temporal lobe epilepsy; Bitemporal epilepsy
Tags
International impact, Reviewed
Změněno: 31/3/2020 22:19, Mgr. Pavla Foltynová, Ph.D.
Abstract
V originále
Objective: The main aim of this study was to investigate the potential differences in terms of interictal high frequency oscillations (HFOs) between both hippocampi in unilateral (U-MTLE) and bilateral mesial temporal lobe epilepsy (B-MTLE). Methods: Sixteen patients with MTLE underwent bilateral hippocampal depth electrode implantation as part of epilepsy surgery evaluation. Interictal HFOs were detected automatically. The analyses entail comparisons of the rates and spatial distributions of ripples and fast ripples (FR) in hippocampi and amygdalae, with respect to the eventual finding of hippocampal sclerosis (HS). Results: In U-MTLE, higher ripple and FR rates were found in the hippocampi ipsilateral to the seizure onset than in the contralateral hippocampi. Non-epileptic hippocampi in U-MTLE were distinguished by significantly lower ripple rate than in the remaining analyzed hippocampi. There were not differences between the hippocampi in B-MTLE. In the hippocampi with proven HS, higher FR rates were observed in the ventral than in the dorsal parts. Conclusions: Non-epileptic hippocampi in U-MTLE demonstrated significantly lower ripple rates than those epileptic in U-MTLE and B-MTLE. Significance: Low interictal HFO occurrence might be considered as a marker of the non-epileptic hippocampi in MTLE. (C) 2019 Published by Elsevier B.V. on behalf of International Federation of Clinical Neurophysiology.
Links
| ROZV/24/LF/2018, interní kód MU |
|