TŘÍSKOVÁ, Iveta, Libuše TRNKOVÁ, Iva KEJNOVSKÁ and Michaela VORLÍČKOVÁ. Electrochemical and Spectral Analysis of Cytosine-rich Nonamers. In Tomáš Navrátil, Miroslav Fojta a Karolina Schwarzová. XXXIX. Moderní elektrochemické metody-sborník přednášek. 1st ed. Ústí nad Labem: Srsenová Lenka-Best servis Ústí nad Labem, 2019, p. 209-212. ISBN 978-80-905221-7-6.
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Basic information
Original name Electrochemical and Spectral Analysis of Cytosine-rich Nonamers
Name in Czech Elektrochemická a spektrální analýza nonamerú bohatých na cytosin
Authors TŘÍSKOVÁ, Iveta (203 Czech Republic, belonging to the institution), Libuše TRNKOVÁ (203 Czech Republic, guarantor), Iva KEJNOVSKÁ (203 Czech Republic) and Michaela VORLÍČKOVÁ (203 Czech Republic).
Edition 1. vyd. Ústí nad Labem, XXXIX. Moderní elektrochemické metody-sborník přednášek, p. 209-212, 4 pp. 2019.
Publisher Srsenová Lenka-Best servis Ústí nad Labem
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10405 Electrochemistry
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
RIV identification code RIV/00216224:14310/19:00110318
Organization unit Faculty of Science
ISBN 978-80-905221-7-6
UT WoS 000583689900049
Keywords (in Czech) ODN bohaté na cytosin; i-motiv;, voltametrie s lineární polarizací elektrody; eliminační voltametrie s lineárním scanem; CD spektra; polyakrylamidová elektroforéza
Keywords in English C-rich ODN; i-motif; Linear sweep voltammetry; Elimination voltammetry with linear scan; CD spectra; Polyacrylamide electrophoresis
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 31/1/2024 17:29.
Abstract
Conformational properties of nucleic acid fragments are strongly dependent on nucleotide sequences. The C-rich ODNs can adopt different secondary structures which are held together by hemiprotonated and intercalated cytosine base pairs (C.C+). These structures, so called i-motifs, were investigated in DNA nonamers with 6C by both electrochemical (voltammetry and electrophoresis) and spectral (absorption UV spectra and circular dichroism) methods. The application EVLS (elimination voltammetry with linear scan) procedure to the reduction signals of cytosine (C) and adenine (A) on a hanging mercury drop electrode revealed different conformations of studied nonamers.
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