SCHUTZ, Katharina, Diana ALECSANDRU, Bodo GRIMBACHER, Jamanda HADDOCK, Annemarie BRUINING, Gertjan DRIESSEN, Esther DE VRIES, Peter M. VAN HAGEN, Ieneke HARTMANN, Francesco FRAIOLI, Cinzia MILITO, Milica MITREVSKI, Isabella QUINTI, Goffredo SERRA, Peter KELLEHER, Michael LOEBINGER, Jiří LITZMAN, Věra POSTRÁNECKÁ, Vojtěch THON, Judith BABAR, Alison M. CONDLIFFE, Andrew EXLEY, Dinakantha KUMARARATNE, Nick SCREATON, Alison JONES, Maria P. BONDIONI, Vassilios LOUGARIS, Alessandro PLEBANI, Annarosa SORESINA, Cesare SIRIGNANO, Giuseppe SPADARO, Nermeen GALAL, Luis I. GONZALEZ-GRANADO, Sabine DETTMER, Robert STIRLING, Helen CHAPEL, Mary LUCAS, Smita PATEL, Claire-Michele FARBER, Isabelle MEYTS, Arpan K. BANERJEE, Scott HACKETT, John R. HURST, Klaus WARNATZ, Benjamin GATHMANN and Ulrich BAUMANN. Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. Journal of Clinical Immunology. New York: Springer, 2019, vol. 39, No 1, p. 45-54. ISSN 0271-9142. Available from: https://dx.doi.org/10.1007/s10875-018-0577-9. |
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@article{1549656, author = {Schutz, Katharina and Alecsandru, Diana and Grimbacher, Bodo and Haddock, Jamanda and Bruining, Annemarie and Driessen, Gertjan and de Vries, Esther and van Hagen, Peter M. and Hartmann, Ieneke and Fraioli, Francesco and Milito, Cinzia and Mitrevski, Milica and Quinti, Isabella and Serra, Goffredo and Kelleher, Peter and Loebinger, Michael and Litzman, Jiří and Postránecká, Věra and Thon, Vojtěch and Babar, Judith and Condliffe, Alison M. and Exley, Andrew and Kumararatne, Dinakantha and Screaton, Nick and Jones, Alison and Bondioni, Maria P. and Lougaris, Vassilios and Plebani, Alessandro and Soresina, Annarosa and Sirignano, Cesare and Spadaro, Giuseppe and Galal, Nermeen and GonzalezandGranado, Luis I. and Dettmer, Sabine and Stirling, Robert and Chapel, Helen and Lucas, Mary and Patel, Smita and Farber, ClaireandMichele and Meyts, Isabelle and Banerjee, Arpan K. and Hackett, Scott and Hurst, John R. and Warnatz, Klaus and Gathmann, Benjamin and Baumann, Ulrich}, article_location = {New York}, article_number = {1}, doi = {http://dx.doi.org/10.1007/s10875-018-0577-9}, keywords = {Chest CT; CVID; primary antibody deficiency; bronchiectasis; bronchial pathology}, language = {eng}, issn = {0271-9142}, journal = {Journal of Clinical Immunology}, title = {Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group}, url = {https://link.springer.com/article/10.1007%2Fs10875-018-0577-9}, volume = {39}, year = {2019} }
TY - JOUR ID - 1549656 AU - Schutz, Katharina - Alecsandru, Diana - Grimbacher, Bodo - Haddock, Jamanda - Bruining, Annemarie - Driessen, Gertjan - de Vries, Esther - van Hagen, Peter M. - Hartmann, Ieneke - Fraioli, Francesco - Milito, Cinzia - Mitrevski, Milica - Quinti, Isabella - Serra, Goffredo - Kelleher, Peter - Loebinger, Michael - Litzman, Jiří - Postránecká, Věra - Thon, Vojtěch - Babar, Judith - Condliffe, Alison M. - Exley, Andrew - Kumararatne, Dinakantha - Screaton, Nick - Jones, Alison - Bondioni, Maria P. - Lougaris, Vassilios - Plebani, Alessandro - Soresina, Annarosa - Sirignano, Cesare - Spadaro, Giuseppe - Galal, Nermeen - Gonzalez-Granado, Luis I. - Dettmer, Sabine - Stirling, Robert - Chapel, Helen - Lucas, Mary - Patel, Smita - Farber, Claire-Michele - Meyts, Isabelle - Banerjee, Arpan K. - Hackett, Scott - Hurst, John R. - Warnatz, Klaus - Gathmann, Benjamin - Baumann, Ulrich PY - 2019 TI - Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group JF - Journal of Clinical Immunology VL - 39 IS - 1 SP - 45-54 EP - 45-54 PB - Springer SN - 02719142 KW - Chest CT KW - CVID KW - primary antibody deficiency KW - bronchiectasis KW - bronchial pathology UR - https://link.springer.com/article/10.1007%2Fs10875-018-0577-9 L2 - https://link.springer.com/article/10.1007%2Fs10875-018-0577-9 N2 - Studies of chest computed tomography (CT) in patients with primary antibody deficiency syndromes (ADS) suggest a broad range of bronchial pathology. However, there are as yet no multicentre studies to assess the variety of bronchial pathology in this patient group. One of the underlying reasons is the lack of a consensus methodology, a prerequisite to jointly document chest CT findings. We aimed to establish an international platform for the evaluation of bronchial pathology as assessed by chest CT and to describe the range of bronchial pathologies in patients with antibody deficiency. Ffteen immunodeficiency centres from 9 countries evaluated chest CT scans of patients with ADS using a predefined list of potential findings including an extent score for bronchiectasis. Data of 282 patients with ADS were collected. Patients with common variable immunodeficiency disorders (CVID) comprised the largest subgroup (232 patients, 82.3%). Eighty percent of CVID patients had radiological evidence of bronchial pathology including bronchiectasis in 61%, bronchial wall thickening in 44% and mucus plugging in 29%. Bronchiectasis was detected in 44% of CVID patients aged less than 20years. Cough was a better predictor for bronchiectasis than spirometry values. Delay of diagnosis as well as duration of disease correlated positively with presence of bronchiectasis. The use of consensus diagnostic criteria and a pre-defined list of bronchial pathologies allows for comparison of chest CT data in multicentre studies. Our data suggest a high prevalence of bronchial pathology in CVID due to late diagnosis or duration of disease. ER -
SCHUTZ, Katharina, Diana ALECSANDRU, Bodo GRIMBACHER, Jamanda HADDOCK, Annemarie BRUINING, Gertjan DRIESSEN, Esther DE VRIES, Peter M. VAN HAGEN, Ieneke HARTMANN, Francesco FRAIOLI, Cinzia MILITO, Milica MITREVSKI, Isabella QUINTI, Goffredo SERRA, Peter KELLEHER, Michael LOEBINGER, Jiří LITZMAN, Věra POSTRÁNECKÁ, Vojtěch THON, Judith BABAR, Alison M. CONDLIFFE, Andrew EXLEY, Dinakantha KUMARARATNE, Nick SCREATON, Alison JONES, Maria P. BONDIONI, Vassilios LOUGARIS, Alessandro PLEBANI, Annarosa SORESINA, Cesare SIRIGNANO, Giuseppe SPADARO, Nermeen GALAL, Luis I. GONZALEZ-GRANADO, Sabine DETTMER, Robert STIRLING, Helen CHAPEL, Mary LUCAS, Smita PATEL, Claire-Michele FARBER, Isabelle MEYTS, Arpan K. BANERJEE, Scott HACKETT, John R. HURST, Klaus WARNATZ, Benjamin GATHMANN and Ulrich BAUMANN. Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. \textit{Journal of Clinical Immunology}. New York: Springer, 2019, vol.~39, No~1, p.~45-54. ISSN~0271-9142. Available from: https://dx.doi.org/10.1007/s10875-018-0577-9.
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