ŠEVČÍKOVÁ, Sabina, Jiri MINARIK, Martin STORK, Tomas JELINEK, Ludek POUR and Roman HAJEK. Extramedullary disease in multiple myeloma - controversies and future directions. BLOOD REVIEWS. EDINBURGH: CHURCHILL LIVINGSTONE, 2019, vol. 36, JUL 2019, p. 32-39. ISSN 0268-960X. Available from: https://dx.doi.org/10.1016/j.blre.2019.04.002.
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Basic information
Original name Extramedullary disease in multiple myeloma - controversies and future directions
Authors ŠEVČÍKOVÁ, Sabina (203 Czech Republic, guarantor, belonging to the institution), Jiri MINARIK (203 Czech Republic), Martin STORK (203 Czech Republic), Tomas JELINEK (203 Czech Republic), Ludek POUR (203 Czech Republic) and Roman HAJEK (203 Czech Republic).
Edition BLOOD REVIEWS, EDINBURGH, CHURCHILL LIVINGSTONE, 2019, 0268-960X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30205 Hematology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.823
RIV identification code RIV/00216224:14110/19:00108508
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.blre.2019.04.002
UT WoS 000475721700004
Keywords in English Multiple myeloma; Extramedullary disease; Treatment; Resistance; Biomarker
Tags 14110518, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 4/3/2020 15:32.
Abstract
Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.
Links
MUNI/A/1553/2018, interní kód MUName: Genetické, environmentální a tkáňové charakteristiky vybraných patologických stavů a nemocí (Acronym: genetika; stres; biomateriály; tkáňové kultury)
Investor: Masaryk University, Category A
NV17-29343A, research and development projectName: Analýza mikroprostředí kostní dřeně u extramedulárního relapsu mnohočetného myelomu
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