Extramedullary disease in multiple myeloma - controversies and
future directions

J 2019

Extramedullary disease in multiple myeloma - controversies and future directions

ŠEVČÍKOVÁ, Sabina, Jiri MINARIK, Martin STORK, Tomas JELINEK, Ludek POUR et. al.

Basic information

Original name

Extramedullary disease in multiple myeloma - controversies and future directions

Authors

ŠEVČÍKOVÁ, Sabina (203 Czech Republic, guarantor, belonging to the institution), Jiri MINARIK (203 Czech Republic), Martin STORK (203 Czech Republic), Tomas JELINEK (203 Czech Republic), Ludek POUR (203 Czech Republic) and Roman HAJEK (203 Czech Republic)

Edition

BLOOD REVIEWS, EDINBURGH, CHURCHILL LIVINGSTONE, 2019, 0268-960X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30205 Hematology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.823

RIV identification code

RIV/00216224:14110/19:00108508

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.blre.2019.04.002

UT WoS

000475721700004

Keywords in English

Multiple myeloma; Extramedullary disease; Treatment; Resistance; Biomarker

Abstract

V originále

Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.

Links

MUNI/A/1553/2018, interní kód MU

Name: Genetické, environmentální a tkáňové charakteristiky vybraných patologických stavů a nemocí (Acronym: genetika; stres; biomateriály; tkáňové kultury)

Investor: Masaryk University, Category A

NV17-29343A, research and development project

Name: Analýza mikroprostředí kostní dřeně u extramedulárního relapsu mnohočetného myelomu

Citovat

ŠEVČÍKOVÁ, Sabina, Jiri MINARIK, Martin STORK, Tomas JELINEK, Ludek POUR and Roman HAJEK. Extramedullary disease in multiple myeloma - controversies and future directions. BLOOD REVIEWS. EDINBURGH: CHURCHILL LIVINGSTONE, 2019, vol. 36, JUL 2019, p. 32-39. ISSN 0268-960X. Available from: https://dx.doi.org/10.1016/j.blre.2019.04.002.

@article{1552256,
   author = {Ševčíková, Sabina and Minarik, Jiri and Stork, Martin and Jelinek, Tomas and Pour, Ludek and Hajek, Roman},
   article_location = {EDINBURGH},
   article_number = {JUL 2019},
   doi = {http://dx.doi.org/10.1016/j.blre.2019.04.002},
   keywords = {Multiple myeloma; Extramedullary disease; Treatment; Resistance; Biomarker},
   language = {eng},
   issn = {0268-960X},
   journal = {BLOOD REVIEWS},
   title = {Extramedullary disease in multiple myeloma - controversies and future directions},
   url = {http://dx.doi.org/10.1016/j.blre.2019.04.002},
   volume = {36},
   year = {2019}
}

TY  - JOUR
ID  - 1552256
AU  - Ševčíková, Sabina - Minarik, Jiri - Stork, Martin - Jelinek, Tomas - Pour, Ludek - Hajek, Roman
PY  - 2019
TI  - Extramedullary disease in multiple myeloma - controversies and future directions
JF  - BLOOD REVIEWS
VL  - 36
IS  - JUL 2019
SP  - 32-39
EP  - 32-39
PB  - CHURCHILL LIVINGSTONE
SN  - 0268960X
KW  - Multiple myeloma
KW  - Extramedullary disease
KW  - Treatment
KW  - Resistance
KW  - Biomarker
UR  - http://dx.doi.org/10.1016/j.blre.2019.04.002
L2  - http://dx.doi.org/10.1016/j.blre.2019.04.002
N2  - Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.
ER  -

ŠEVČÍKOVÁ, Sabina, Jiri MINARIK, Martin STORK, Tomas JELINEK, Ludek POUR and Roman HAJEK. Extramedullary disease in multiple myeloma - controversies and future directions. \textit{BLOOD REVIEWS}. EDINBURGH: CHURCHILL LIVINGSTONE, 2019, vol.~36, JUL 2019, p.~32-39. ISSN~0268-960X. Available from: https://dx.doi.org/10.1016/j.blre.2019.04.002.

Detailed Information on Publication Record