Intralipid infusion in paediatric patient with quetiapine and
lamotrigine intoxication

J 2019

Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication

KLUČKA, Jozef, Tomáš JUŘENČÁK, Martina KOSINOVÁ, Petr ŠTOURAČ, Milan KRATOCHVÍL et. al.

Basic information

Original name

Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication

Authors

KLUČKA, Jozef (703 Slovakia, belonging to the institution), Tomáš JUŘENČÁK (203 Czech Republic, belonging to the institution), Martina KOSINOVÁ (203 Czech Republic, belonging to the institution), Petr ŠTOURAČ (203 Czech Republic, guarantor, belonging to the institution), Milan KRATOCHVÍL (703 Slovakia, belonging to the institution), Yvona SEDLÁČKOVÁ (203 Czech Republic), Tomáš NAVRÁTIL (203 Czech Republic), Daniela PELCLOVÁ (203 Czech Republic) and Petr JABANDŽIEV (203 Czech Republic, belonging to the institution)

Edition

Monatshefte fur Chemie, Wien, Springer Wien, 2019, 0026-9247

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30209 Paediatrics

Country of publisher

Austria

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.349

RIV identification code

RIV/00216224:14110/19:00110701

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s00706-019-02423-5

UT WoS

000482907600022

Keywords in English

Antipsychotic drug intoxication; Life-threatening arrhythmia; Lipid resuscitation; Paediatric patient

Abstract

V originále

We present a case of the acute intoxication of a 17-year-old patient after ingestion of 6 g of quetiapine in combination with 1 g of lamotrigine. Due to the severe tachycardia, hypertension, and prolonged QTc without improvement after standard treatment, the patient was treated with Intralipid 20% intravenous infusion recommended by the Toxicologic Information Centre. After lipid infusion, the QTc rapidly normalised and tachycardia resolved to sinus rhythm. The patient was transferred to psychiatry intensive care on the third day after admission. [GRAPHICS] .

Links

MUNI/A/1111/2018, interní kód MU

Name: Videolaryngoskopie vs. přímá laryngoskopie vliv na efektivitu intubace: randomizovaná kontrolovaná studie (Acronym: VidoeLarynx)

Investor: Masaryk University, Category A

Citovat

KLUČKA, Jozef, Tomáš JUŘENČÁK, Martina KOSINOVÁ, Petr ŠTOURAČ, Milan KRATOCHVÍL, Yvona SEDLÁČKOVÁ, Tomáš NAVRÁTIL, Daniela PELCLOVÁ and Petr JABANDŽIEV. Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication. Monatshefte fur Chemie. Wien: Springer Wien, 2019, vol. 150, No 9, p. 1711-1714. ISSN 0026-9247. Available from: https://dx.doi.org/10.1007/s00706-019-02423-5.

@article{1557936,
   author = {Klučka, Jozef and Juřenčák, Tomáš and Kosinová, Martina and Štourač, Petr and Kratochvíl, Milan and Sedláčková, Yvona and Navrátil, Tomáš and Pelclová, Daniela and Jabandžiev, Petr},
   article_location = {Wien},
   article_number = {9},
   doi = {http://dx.doi.org/10.1007/s00706-019-02423-5},
   keywords = {Antipsychotic drug intoxication; Life-threatening arrhythmia; Lipid resuscitation; Paediatric patient},
   language = {eng},
   issn = {0026-9247},
   journal = {Monatshefte fur Chemie},
   title = {Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication},
   url = {http://dx.doi.org/10.1007/s00706-019-02423-5},
   volume = {150},
   year = {2019}
}

TY  - JOUR
ID  - 1557936
AU  - Klučka, Jozef - Juřenčák, Tomáš - Kosinová, Martina - Štourač, Petr - Kratochvíl, Milan - Sedláčková, Yvona - Navrátil, Tomáš - Pelclová, Daniela - Jabandžiev, Petr
PY  - 2019
TI  - Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication
JF  - Monatshefte fur Chemie
VL  - 150
IS  - 9
SP  - 1711-1714
EP  - 1711-1714
PB  - Springer Wien
SN  - 00269247
KW  - Antipsychotic drug intoxication
KW  - Life-threatening arrhythmia
KW  - Lipid resuscitation
KW  - Paediatric patient
UR  - http://dx.doi.org/10.1007/s00706-019-02423-5
L2  - http://dx.doi.org/10.1007/s00706-019-02423-5
N2  - We present a case of the acute intoxication of a 17-year-old patient after ingestion of 6 g of quetiapine in combination with 1 g of lamotrigine. Due to the severe tachycardia, hypertension, and prolonged QTc without improvement after standard treatment, the patient was treated with Intralipid 20% intravenous infusion recommended by the Toxicologic Information Centre. After lipid infusion, the QTc rapidly normalised and tachycardia resolved to sinus rhythm. The patient was transferred to psychiatry intensive care on the third day after admission. [GRAPHICS] .
ER  -

KLUČKA, Jozef, Tomáš JUŘENČÁK, Martina KOSINOVÁ, Petr ŠTOURAČ, Milan KRATOCHVÍL, Yvona SEDLÁČKOVÁ, Tomáš NAVRÁTIL, Daniela PELCLOVÁ and Petr JABANDŽIEV. Intralipid infusion in paediatric patient with quetiapine and lamotrigine intoxication. \textit{Monatshefte fur Chemie}. Wien: Springer Wien, 2019, vol.~150, No~9, p.~1711-1714. ISSN~0026-9247. Available from: https://dx.doi.org/10.1007/s00706-019-02423-5.

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