J 2019

Impact of contralateral carotid stenosis on brain tissue oxygenation during carotid endarterectomy

LUKEŠ, Marek, Martin HELÁN, Vladimír ŠRÁMEK, Jana PAVLÍKOVÁ, Robert STAFFA et. al.

Basic information

Original name

Impact of contralateral carotid stenosis on brain tissue oxygenation during carotid endarterectomy

Name in Czech

Vliv stenózy kontralaterální karotidy na tkáňovou oxygenaci mozku během karotické endarterektomie

Authors

LUKEŠ, Marek (203 Czech Republic, belonging to the institution), Martin HELÁN (203 Czech Republic, belonging to the institution), Vladimír ŠRÁMEK (203 Czech Republic, belonging to the institution), Jana PAVLÍKOVÁ (203 Czech Republic), Robert STAFFA (203 Czech Republic, belonging to the institution) and Pavel SUK (203 Czech Republic, guarantor, belonging to the institution)

Edition

Cor et Vasa, Elsevier, 2019, 0010-8650

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14110/19:00110769

Organization unit

Faculty of Medicine

DOI

UT WoS

000480675500008

Keywords (in Czech)

Blízká infračervená spektroskopie; Cerebrovaskulární monitorace; Cerebrální oxymetrie; Ischemie mozku; Karotická endarterektomie

Keywords in English

Carotid endarterectomy; Cerebral ischemia; Cerebral oximetry; Cerebrovascular monitoring; Near-infrared spectroscopy

Tags

Tags

International impact, Reviewed
Změněno: 11/5/2020 13:09, Mgr. Tereza Miškechová

Abstract

V originále

Background: Cerebral oximetry (rSO(2)) seems to be a promising technique for assessment the adequacy of cerebral oxygen delivery during carotid endarterectomy (CEA). The purpose of this study was to evaluate the association of the severity of contralateral (non-operated) carotid artery stenosis and the magnitude of rSO(2) changes during CEA. Methods: rSO(2) was monitored in 38 patients undergoing CEA under regional anesthesia. Patients were retrospectively assigned to one of two groups: with (Gdef) or without (Gnodef) change in neurological status. Baseline rSO(2) values (rSO(2) base), average (rSO(2)avg) and minimal (rSO(2)min) values during 3 minutes after clamping, and rSO(2) change after clamping (Delta rSO(2)avg and Delta rSO(2)min) were compared between both groups. The influence of contralateral carotid artery stenosis on rSO(2) was assessed by correlation. Data are presented as median (IQR). Results: Neurologic deterioration has developed in 4 patients. We did not find any statistical difference in rSO(2) values between Gdef a Gnodef on operated side - rSO(2) base was 79 (75-87) in Gnodef and 79 (64-90) in Gdef (p = 0.84), rSO(2) min 74 (65-81) in Gnodef and 75 (59-90) in Gdef (p = 0.70), and Delta rSO(2) min 6 (2-13) in Gnodef and 2 (0-6) in Gdef (p = 0.15). Similarly, there was not any difference between groups if rSO(2) was measured on contralateral side. We showed that non-operated ACI stenosis was a risk factor for developing of perioperative neurological deficit, but we did not demonstrate any influence of non-operated ACI stenosis severity on rSO(2) values. Conclusion: We did not prove any association between the severity of contralateral carotid artery stenosis and the magnitude of rSO(2) changes during CEA. Cerebral oximetry was not able to predict the development of neurologic deficit during CEA.