MRÓZEK, Jan, Tereza NEČASOVÁ, Michal SVOBODA, Iveta ŠIMKOVÁ and Pavel JANSA. Prediction Score for persisting perfusion defects after pulmonary embolism. Biomedical Papers. Olomouc: Univerzita Palackého v Olomouci, 2020, vol. 164, No 4, p. 394-400. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2019.033.
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Basic information
Original name Prediction Score for persisting perfusion defects after pulmonary embolism
Authors MRÓZEK, Jan (203 Czech Republic), Tereza NEČASOVÁ (203 Czech Republic, belonging to the institution), Michal SVOBODA (203 Czech Republic, belonging to the institution), Iveta ŠIMKOVÁ (203 Czech Republic) and Pavel JANSA (203 Czech Republic).
Edition Biomedical Papers, Olomouc, Univerzita Palackého v Olomouci, 2020, 1213-8118.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30203 Respiratory systems
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.245
RIV identification code RIV/00216224:14110/20:00115108
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.5507/bp.2019.033
UT WoS 000604951200007
Keywords in English pulmonary embolism; prediction score; perfusion defects; reperfusion; risk score; classification
Tags 14119612, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 27/1/2021 10:26.
Abstract
Long-term persistence of perfusion defect after pulmonary embolism (PE) may lead to the development of chronic thromboembolic pulmonary hypertension. Identification of patients at risk of such a complication using a scoring system would be beneficial in clinical practice. Here, we aimed to derive a score for predicting persistence of perfusion defects after PE.Methods. 83 patients after PE were re-examined 6, 12 and 24 months after the PE episode. Data collected at the time of PE and perfusion status during follow-ups were used for modelling perfusion defects persistence using the Cox proportional hazards model and validated using bootstrap method.Results. A simple scoring system utilizing two variables (hemoglobin levels and age at the time of PE) was developed. Patients with hemoglobin levels over 140 g/L who were older than 65 years were at the highest risk of perfusion defects; in patients with the same hemoglobin levels and age {\&}lt; 65 years, the risk was reduced by 79{\%}, and by 89{\%} in patients with hemoglobin {\&}lt; 140 g/L.Conclusion. The proposed scoring system may be useful in clinical practice for identifying patients with high risk of persisting perfusion defects, flagging them for closer follow up, thus improving the effectiveness of long-term treatment of patients after PE.
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