Processing of Emotions in Functional Movement Disorder: An
Exploratory fMRI Study

J 2019

Processing of Emotions in Functional Movement Disorder: An Exploratory fMRI Study

SOJKA, Petr, Jan LOŠÁK, Martin LAMOŠ, Martin BAREŠ, Tomáš KAŠPÁREK et. al.

Basic information

Original name

Processing of Emotions in Functional Movement Disorder: An Exploratory fMRI Study

Authors

SOJKA, Petr (203 Czech Republic, belonging to the institution), Jan LOŠÁK (203 Czech Republic, belonging to the institution), Martin LAMOŠ (203 Czech Republic, belonging to the institution), Martin BAREŠ (203 Czech Republic, belonging to the institution), Tomáš KAŠPÁREK (203 Czech Republic, belonging to the institution), Milan BRÁZDIL (203 Czech Republic, belonging to the institution), Marek BALÁŽ (703 Slovakia, belonging to the institution), Miroslav SVĚTLÁK (203 Czech Republic, belonging to the institution), Jitka KOČVAROVÁ (203 Czech Republic, belonging to the institution) and Jana FIALOVÁ (203 Czech Republic, belonging to the institution)

Edition

FRONTIERS IN NEUROLOGY, LAUSANNE, FRONTIERS MEDIA SA, 2019, 1664-2295

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.889

RIV identification code

RIV/00216224:14110/19:00108518

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3389/fneur.2019.00861

UT WoS

000480730600001

Keywords in English

emotion regulation; functional neurological disorder; neuroimaging; alexithymia; precuneus

Abstract

V originále

Background: Affective dysregulation and impaired cognitive control are implicated in the pathology of functional neurological disorders (FNDs). However, voluntary regulation of emotions has seldom been researched in this group of patients. We hypothesized that patients with FNDs use inefficient voluntary emotion regulation strategies and regulate emotional reactions via increased motor activation. Methods: Fifteen patients with functional movement disorder (FMD) and fifteen healthy subjects matched by age, sex, and education underwent an emotion regulation task in fMRI. For stimuli, we used neutral and negative pictures from the International Affective Picture System. There was no restriction on their emotion regulation strategy. Both patients and healthy subjects were asked about the strategies they had used in a post-scanning interview. Participant levels of depression, trait anxiety, and alexithymia were assessed. Results: There were no significant differences in the emotion regulation strategies used by patients and healthy subjects, nor in levels of reported alexithymia and depression. However, patients showed increased activation in several brain areas when observing negative pictures, notably in the post-central gyrus, precuneus, posterior cingulate cortex (PCC) and cerebellar vermis, and also in their emotion regulation condition, particularly in the precuneus and post-central gyrus. Alexithymia was negatively associated with left insular activation during the observation of unpleasant stimuli only in the patient group. Conclusions: Our findings may implicate areas associated with self-referential processing in voluntary emotional regulation and lower emotional awareness as having a role in patients with functional movement disorders. However, our findings must be replicated with larger sample.

Links

NV16-31457A, research and development project

Name: Neurobiologické mechanismy funkčních neurologických poruch

90062, large research infrastructures

Name: Czech-BioImaging

Citovat

SOJKA, Petr, Jan LOŠÁK, Martin LAMOŠ, Martin BAREŠ, Tomáš KAŠPÁREK, Milan BRÁZDIL, Marek BALÁŽ, Miroslav SVĚTLÁK, Jitka KOČVAROVÁ and Jana FIALOVÁ. Processing of Emotions in Functional Movement Disorder: An Exploratory fMRI Study. FRONTIERS IN NEUROLOGY. LAUSANNE: FRONTIERS MEDIA SA, 2019, vol. 10, AUG 14 2019, p. 1-10. ISSN 1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2019.00861.

@article{1567216,
   author = {Sojka, Petr and Lošák, Jan and Lamoš, Martin and Bareš, Martin and Kašpárek, Tomáš and Brázdil, Milan and Baláž, Marek and Světlák, Miroslav and Kočvarová, Jitka and Fialová, Jana},
   article_location = {LAUSANNE},
   article_number = {AUG 14 2019},
   doi = {http://dx.doi.org/10.3389/fneur.2019.00861},
   keywords = {emotion regulation; functional neurological disorder; neuroimaging; alexithymia; precuneus},
   language = {eng},
   issn = {1664-2295},
   journal = {FRONTIERS IN NEUROLOGY},
   title = {Processing of Emotions in Functional Movement Disorder: An Exploratory fMRI Study},
   url = {http://dx.doi.org/10.3389/fneur.2019.00861},
   volume = {10},
   year = {2019}
}

TY  - JOUR
ID  - 1567216
AU  - Sojka, Petr - Lošák, Jan - Lamoš, Martin - Bareš, Martin - Kašpárek, Tomáš - Brázdil, Milan - Baláž, Marek - Světlák, Miroslav - Kočvarová, Jitka - Fialová, Jana
PY  - 2019
TI  - Processing of Emotions in Functional Movement Disorder: An Exploratory fMRI Study
JF  - FRONTIERS IN NEUROLOGY
VL  - 10
IS  - AUG 14 2019
SP  - 1-10
EP  - 1-10
PB  - FRONTIERS MEDIA SA
SN  - 16642295
KW  - emotion regulation
KW  - functional neurological disorder
KW  - neuroimaging
KW  - alexithymia
KW  - precuneus
UR  - http://dx.doi.org/10.3389/fneur.2019.00861
L2  - http://dx.doi.org/10.3389/fneur.2019.00861
N2  - Background: Affective dysregulation and impaired cognitive control are implicated in the pathology of functional neurological disorders (FNDs). However, voluntary regulation of emotions has seldom been researched in this group of patients. We hypothesized that patients with FNDs use inefficient voluntary emotion regulation strategies and regulate emotional reactions via increased motor activation. Methods: Fifteen patients with functional movement disorder (FMD) and fifteen healthy subjects matched by age, sex, and education underwent an emotion regulation task in fMRI. For stimuli, we used neutral and negative pictures from the International Affective Picture System. There was no restriction on their emotion regulation strategy. Both patients and healthy subjects were asked about the strategies they had used in a post-scanning interview. Participant levels of depression, trait anxiety, and alexithymia were assessed. Results: There were no significant differences in the emotion regulation strategies used by patients and healthy subjects, nor in levels of reported alexithymia and depression. However, patients showed increased activation in several brain areas when observing negative pictures, notably in the post-central gyrus, precuneus, posterior cingulate cortex (PCC) and cerebellar vermis, and also in their emotion regulation condition, particularly in the precuneus and post-central gyrus. Alexithymia was negatively associated with left insular activation during the observation of unpleasant stimuli only in the patient group. Conclusions: Our findings may implicate areas associated with self-referential processing in voluntary emotional regulation and lower emotional awareness as having a role in patients with functional movement disorders. However, our findings must be replicated with larger sample.
ER  -

SOJKA, Petr, Jan LOŠÁK, Martin LAMOŠ, Martin BAREŠ, Tomáš KAŠPÁREK, Milan BRÁZDIL, Marek BALÁŽ, Miroslav SVĚTLÁK, Jitka KOČVAROVÁ and Jana FIALOVÁ. Processing of Emotions in Functional Movement Disorder: An Exploratory fMRI Study. \textit{FRONTIERS IN NEUROLOGY}. LAUSANNE: FRONTIERS MEDIA SA, 2019, vol.~10, AUG 14 2019, p.~1-10. ISSN~1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2019.00861.

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