CHOCHOLOVÁ, Eva, Dana FIALOVÁ, Eva DROZDOVÁ, Radim SKOUPÝ, Kristýna BRZOBOHATÁ, Barbora ZWINSOVÁ, Petra VÍDEŇSKÁ and Václav CHOCHOLA. Looking at the health of past populations through the lens of human dental calculus. In The Biomania Student Scientific Meeting & EUSynBioS Symposium 2019. 2019. ISBN 978-80-210-9373-7.
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Basic information
Original name Looking at the health of past populations through the lens of human dental calculus
Authors CHOCHOLOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Dana FIALOVÁ (203 Czech Republic, belonging to the institution), Eva DROZDOVÁ (203 Czech Republic, belonging to the institution), Radim SKOUPÝ (203 Czech Republic), Kristýna BRZOBOHATÁ (203 Czech Republic, belonging to the institution), Barbora ZWINSOVÁ (203 Czech Republic, belonging to the institution), Petra VÍDEŇSKÁ (203 Czech Republic, belonging to the institution) and Václav CHOCHOLA (203 Czech Republic, belonging to the institution).
Edition The Biomania Student Scientific Meeting & EUSynBioS Symposium 2019, 2019.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10608 Biochemistry and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/19:00110957
Organization unit Faculty of Science
ISBN 978-80-210-9373-7
Keywords (in Czech) starobylá DNA; aDNA; patogen; zubní kámen; metagenomika
Keywords in English ancient DNA; aDNA; pathogen; dental calculus; metagenomics
Tags International impact, Reviewed
Changed by Changed by: Mgr. Eva Chocholová, učo 423026. Changed: 27/4/2023 16:41.
Abstract
Connection of ancient human dental calculus and molecular biology has so far brought up more questions than answers. Dental calculus is a calcified dental plaque and as such, it is mostly composed of bacteria and their products. This opens a door to the research of oral health as well as pathogens found in blood or respiratory system. The presented study shows the potential of molecular research of ancient human dental calculus in connection with health and the problems with authentication of acquired results. Several potential pathogens were detected by sequencing of 16S rDNA in Early Medieval specimens, but an even greater quantity of contaminating organisms was found. How does that change the usefulness of the applied approach? Is there a right way for the interpretation of metagenomic data derived from ancient samples?
Links
MUNI/C/1717/2016, interní kód MUName: Identifikace bakteriálně přenosných nemocí z historického zubního kamene
Investor: Masaryk University, Rector's Program
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