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@article{1574056,
author = {Michal, Michael and Agaimy, Abbas and Folpe, Andrew L. and Staniczková Zambo, Iva and Kebrle, Radek and Horch, Raymund E. and Kinkor, Zdenek and Svajdler, Marian and Vanecek, Tomas and Heidenreich, Filip and Kazakov, Dmitry V. and Michalova, Kvetoslava and Hadravsky, Ladislav and Michal, Michal},
article_location = {PHILADELPHIA},
article_number = {2},
doi = {http://dx.doi.org/10.1097/PAS.0000000000001182},
keywords = {tenosynovitis with psammomatous calcifications; idiopathic calcifying tenosynovitis; calcific periarthritis; calcifying tendinitis; tumoral calcinosis; psammoma bodies},
language = {eng},
issn = {0147-5185},
journal = {The American Journal of Surgical Pathology},
title = {Tenosynovitis With Psammomatous Calcifications A Distinctive Trauma-Associated Subtype of Idiopathic Calcifying Tenosynovitis With a Predilection for the Distal extremities of Middle-Aged Women-A Report of 23 Cases},
url = {http://dx.doi.org/10.1097/PAS.0000000000001182},
volume = {43},
year = {2019}
}
TY - JOUR
ID - 1574056
AU - Michal, Michael - Agaimy, Abbas - Folpe, Andrew L. - Staniczková Zambo, Iva - Kebrle, Radek - Horch, Raymund E. - Kinkor, Zdenek - Svajdler, Marian - Vanecek, Tomas - Heidenreich, Filip - Kazakov, Dmitry V. - Michalova, Kvetoslava - Hadravsky, Ladislav - Michal, Michal
PY - 2019
TI - Tenosynovitis With Psammomatous Calcifications A Distinctive Trauma-Associated Subtype of Idiopathic Calcifying Tenosynovitis With a Predilection for the Distal extremities of Middle-Aged Women-A Report of 23 Cases
JF - The American Journal of Surgical Pathology
VL - 43
IS - 2
SP - 261-267
EP - 261-267
PB - LIPPINCOTT WILLIAMS & WILKINS
SN - 01475185
KW - tenosynovitis with psammomatous calcifications
KW - idiopathic calcifying tenosynovitis
KW - calcific periarthritis
KW - calcifying tendinitis
KW - tumoral calcinosis
KW - psammoma bodies
UR - http://dx.doi.org/10.1097/PAS.0000000000001182
L2 - http://dx.doi.org/10.1097/PAS.0000000000001182
N2 - The term "idiopathic calcifying tenosynovitis" (ICT) refers to a clinically and radiologically defined syndrome of pain and tendinous calcifications, most often involving the shoulder joint. A distinctive subset of ICT cases, termed "tenosynovitis with psammomatous calcifications" (TPC), occurs in the distal extremities and shows characteristic morphology, in particular psammomatous calcifications. As only 14 cases have been reported to date, TPC remains poorly recognized by both pathologists and clinicians. Twenty-three well-characterized cases of TPC along with all available radiologic and clinical information, including follow-up, were collected. Cases occurred in 21 females and 1 male (1 patient of unknown sex), aged 16 to 75 years (mean: 41), and almost exclusively involved the fingers and toes, except for one case in the elbow and one in the knee joint. The lesions ranged from 2 to 30 mm in size (mean: 10 mm). Pain was the most common presenting symptom (12/16 patients). A history of trauma or repetitive activity was present in 6 of 15 patients. None of the individuals was known to have disorders in calcium or phosphate metabolism. Radiographic studies showed a nonspecific, calcified mass. Typical morphologic features of TPC were invariably present, with degenerating tendinous tissue containing psammomatous calcifications, surrounded by a variably cellular, CD68/CD163/CD4-positive histiocyte-rich granulomatous host reaction. HUMARA assay in one case showed a polyclonal pattern. Clinical follow-up (19 patients; mean: 5.2 y; range: 1 to 14 y) showed no local recurrences. In this, the largest study of TPC to date, we confirm striking predilection of this distinctive pseudoneoplasm for the fingers and toes of young to middle-aged women. TPC should be rigorously distinguished from other forms of ICT, which typically involve large, proximal joints, and show simply dystrophic calcification involving tendinous tissues, and from tumoral calcinosis, which also involves large joints and often is associated with calcium and/or phosphate abnormalities. TPC appears to be related to trauma and/or repetitive activity and is cured with simple excision.
ER -
MICHAL, Michael, Abbas AGAIMY, Andrew L. FOLPE, Iva STANICZKOVÁ ZAMBO, Radek KEBRLE, Raymund E. HORCH, Zdenek KINKOR, Marian SVAJDLER, Tomas VANECEK, Filip HEIDENREICH, Dmitry V. KAZAKOV, Kvetoslava MICHALOVA, Ladislav HADRAVSKY a Michal MICHAL. Tenosynovitis With Psammomatous Calcifications A Distinctive Trauma-Associated Subtype of Idiopathic Calcifying Tenosynovitis With a Predilection for the Distal extremities of Middle-Aged Women-A Report of 23 Cases. \textit{The American Journal of Surgical Pathology}. PHILADELPHIA: LIPPINCOTT WILLIAMS \&{}amp; WILKINS, roč.~43, č.~2, s.~261-267. ISSN~0147-5185. doi:10.1097/PAS.0000000000001182. 2019.
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