Detailed Information on Publication Record
2019
ETR1 Integrates Response to Ethylene and Cytokinins into a Single Multistep Phosphorelay Pathway to Control Root Growth
ŽĎÁRSKÁ, Markéta, Abigail Rubiato CUYACOT, P.T. TARR, Amel YAMOUNE, Agnieszka SZMITKOWSKA et. al.Basic information
Original name
ETR1 Integrates Response to Ethylene and Cytokinins into a Single Multistep Phosphorelay Pathway to Control Root Growth
Authors
ŽĎÁRSKÁ, Markéta (203 Czech Republic, belonging to the institution), Abigail Rubiato CUYACOT (608 Philippines, belonging to the institution), P.T. TARR (840 United States of America), Amel YAMOUNE (12 Algeria, belonging to the institution), Agnieszka SZMITKOWSKA (616 Poland, belonging to the institution), Vendula HRDINOVÁ (203 Czech Republic, belonging to the institution), Zuzana GELOVÁ (203 Czech Republic, belonging to the institution), E.M. MEYEROWITZ (840 United States of America) and Jan HEJÁTKO (203 Czech Republic, guarantor, belonging to the institution)
Edition
Molecular Plant, Cambridge (USA), Cell Press, 2019, 1674-2052
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10608 Biochemistry and molecular biology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 12.084
RIV identification code
RIV/00216224:14740/19:00107755
Organization unit
Central European Institute of Technology
UT WoS
000489132500005
Keywords in English
cytokinin; ethylene; crosstalk; signaling; root development
Tags
International impact, Reviewed
Změněno: 7/10/2024 12:41, Ing. Martina Blahová
Abstract
V originále
Cytokinins and ethylene control plant development via sensors from the histidine kinase (HK) family. However, downstreamsignaling pathways for the key phytohormones are distinct. Here we report that not only cytokinin but also ethylene is able to control root apical meristem (RAM) size through activation of the multi-step phosphorelay (MSP) pathway. We found that both cytokinin and ethylene-dependent RAM shortening requires ethylene binding to ETR1 and the HK activity of ETR1. The receiver domain of ETR1 interacts with MSP signaling intermediates acting downstream of cytokinin receptors, further substantiating the role of ETR1 in MSP signaling. We revealed that both cytokinin and ethylene induce the MSP in similar and distinct cell types with ETR1-mediated ethylene signaling controlling MSP output specifically in the root transition zone. We identified members of the MSP pathway specific and common to both hormones and showed that ETR1-regulated ARR3 controls RAM size. ETR1-mediated MSP spatially differs from canonical CTR1/EIN2/ EIN3 ethylene signaling and is independent of EIN2, indicating that both pathways can be spatially and functionally separated. Furthermore, we demonstrated that canonical ethylene signaling controls MSP responsiveness to cytokinin specifically in the root transition zone, presumably via regulation of ARR10, one of the positive regulators of MSP signaling in Arabidopsis.
Links
| EF16_026/0008446, research and development project |
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| GA15-22000S, research and development project |
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| GJ19-23108Y, research and development project |
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| LQ1601, research and development project |
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| LTAUSA18161, research and development project |
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| MUNI/E/0555/2018, interní kód MU |
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| 90062, large research infrastructures |
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