Detailed Information on Publication Record
2019
Inappropriate conversion of current magnitude to current density may misinterpret results
KULA, Roman, Markéta BÉBAROVÁ, Jiří ŠIMURDA and Michal PÁSEKBasic information
Original name
Inappropriate conversion of current magnitude to current density may misinterpret results
Authors
KULA, Roman (203 Czech Republic, belonging to the institution), Markéta BÉBAROVÁ (203 Czech Republic, guarantor, belonging to the institution), Jiří ŠIMURDA (203 Czech Republic, belonging to the institution) and Michal PÁSEK (203 Czech Republic)
Edition
43rd EWGCCE Meeting, 2019
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30105 Physiology
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 4.045
RIV identification code
RIV/00216224:14110/19:00108532
Organization unit
Faculty of Medicine
ISSN
Keywords in English
current amplitude; current density; capacitance; correlation; normalization
Tags
Tags
International impact, Reviewed
Změněno: 22/4/2020 09:03, Mgr. Tereza Miškechová
Abstract
V originále
The magnitude of ionic current (I, in pA) is usually assumed to increase proportionally to the membrane area roughly estimated by measurement of the membrane capacitance (C, in pF). Hence, to lower differences of data measured in cells with varying cell membrane areas, the current density (J, in pA/pF) is routinely calculated as I/C ratio. However, if the I-C correlation was weak and insignificant, the conversion to J would be inappropriate and, if performed, could considerably change the interpretation of results.
Links
| NV16-30571A, research and development project |
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