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@proceedings{1584716,
author = {Svačinová, Jana and Hidegová, Simona and Sieglová, Helena and Kaščáková, Zuzana and Fabšík, Martin and Jakubík, Juraj and Novák, Jan and Nováková, Zuzana and Hrušková, Jana},
booktitle = {Joint Meeting of the Federation of European Physiological Societies (FEPS) and the Italian Physiological Society (SIF) Bologna (Italy), September 10th – 13th 2019},
keywords = {pulse wave velocity; arterial compliance},
language = {eng},
title = {Beat-to-beat variability of pulse wave velocity},
year = {2019}
}
TY - CONF
ID - 1584716
AU - Svačinová, Jana - Hidegová, Simona - Sieglová, Helena - Kaščáková, Zuzana - Fabšík, Martin - Jakubík, Juraj - Novák, Jan - Nováková, Zuzana - Hrušková, Jana
PY - 2019
TI - Beat-to-beat variability of pulse wave velocity
KW - pulse wave velocity
KW - arterial compliance
N2 - Pulse wave velocity (PWV) increase is a marker of decreased arterial compliance (C). C decreases with increased blood pressure (BP), due to endothelial dysfunction and structural changes of the arterial wall. Increased mean PWV is observed in diabetics as well as in hypertonics. Mean PWV was analysed in many studies, but beat-to-beat changes of the PWV were less described. Aim of this pilot study is analysis of PWV beat-to-beat variability in dependence of body position. PWV was measured in II. type diabetics (DM: 7m/8f, age 68±10 years, BP 158/90±19/9 mmHg) and healthy controls (Con: 5m/6f, age 23±2 years, BP 117/76±9/5 mmHg). PWV was recorded by method based on multichannel full body bioimpedance. Protocol consisted of 6 min of supine (sup) and 6 min of head up tilt in 45°(hut). PWV of left forearm (PWVlf) and left calf (PWVlc) were measured. Variability was counted as mean power spectra of PWV in frequency bands LF (0.04 – 0.15 Hz) and HF (0.15 – 0.5 Hz). Results: LF-PWVlf, HF-PWVlf and HF-PWVlc in sup were higher in DM than in Con. During hut LF-PWVlc and HF-PWVlc increased in both groups; LF-PWVlf and HF-PWVlf increased only in Con. During hut of DM, PWVlf was lower than PWVlc. Decreased ability of arterial wall to dampen blood pressure changes probably could lead to higher PWV variability. This could be caused by hypertension and changed arterial stiffness (differences between groups), or by blood redistribution during body position change (differences between sup/hut and lf/cl). This pilot study showed, that PWV variability was changed by health condition, body position and measured artery position. Clear understanding of mechanism influencing PWV variability requires further study.
ER -
SVAČINOVÁ, Jana, Simona HIDEGOVÁ, Helena SIEGLOVÁ, Zuzana KAŠČÁKOVÁ, Martin FABŠÍK, Juraj JAKUBÍK, Jan NOVÁK, Zuzana NOVÁKOVÁ and Jana HRUŠKOVÁ. Beat-to-beat variability of pulse wave velocity. In \textit{Joint Meeting of the Federation of European Physiological Societies (FEPS) and the Italian Physiological Society (SIF) Bologna (Italy), September 10th – 13th 2019}. 2019. ISSN~1748-1708.
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