Five years of improving diabetes control in Czech children
after the establishment of the population-based childhood
diabetes register ČENDA.

J 2020

Five years of improving diabetes control in Czech children after the establishment of the population-based childhood diabetes register ČENDA.

ŠUMNÍK, Zdeněk, Jitřenka VENHÁČOVÁ, Jaroslav ŠKVOR, Renata POMAHAČOVÁ, Petra KONEČNÁ et. al.

Basic information

Original name

Five years of improving diabetes control in Czech children after the establishment of the population-based childhood diabetes register ČENDA.

Name in Czech

Zvýšení kontroly diabetu u českých dětí 5 let po vytvoření populačního registru diabetu: ČENDA

Authors

Edition

Pediatric Diabetes, Spojené státy americké, Wiley, 2020, 1399-5448

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30209 Paediatrics

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.866

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1111/pedi.12929

UT WoS

000490350900001

Keywords (in Czech)

diabetes; děti

Keywords in English

diabetes; children

Změněno: 5/6/2020 14:28, Mgr. Tereza Miškechová

Abstract

ORIG CZ

V originále

OBJECTIVES: The Czech National Childhood Diabetes Register (ČENDA) is a web-based nationwide database that collects treatment and outcome data in children and adolescents with diabetes. Here, we present data from the first 5 years of ČENDA (2013-2017). METHODS: Data include characteristics of disease onset and annual summaries of key clinical care parameters from every patient treated by participating pediatric diabetes outpatient clinics. RESULTS: The database contains data of 4361 children (aged 0-19 years) from 52 centers (85% of all Czech pediatric patients). Of these, 94% had type 1 diabetes (T1D), 4.5% had genetically proven monogenic or secondary, and 1.5% had type 2 diabetes. In children with T1D, median glycated hemoglobin (HbA1c) decreased throughout the observed period from 66.3 to 61.0 mmol/mol (P < .0001, 95% confidence interval [CI] for change -5.6 to -4 mmol/mol). Consequently, the proportion of children reaching the target therapeutic goal of 58.5 mmol/mol increased from 28% in 2013 to 40% in 2017. The proportion of children treated with insulin pumps (CSII) remained stable over the observed period (25%). In a subanalysis of 1602 patients (long-standing T1D diagnosed before 2011), the main predictors associated with lower HbA1c were treatment with CSII, male sex and care provided at a large diabetes center (>100 patients). CONCLUSIONS: A significant continuous decrease in HbA1c was observed in Czech children over the past 5 years. As this improvement was not accompanied by appreciable changes in the mode of therapy, we assume that the establishment of our nationwide register has itself constituted a stimulus towards improvement in the care process.

In Czech

Autoři popisují výsledky kontroly dětí s diabetes mellitus v České republice po ustavení tzv. registru ČENDA.

Citovat

ŠUMNÍK, Zdeněk, Jitřenka VENHÁČOVÁ, Jaroslav ŠKVOR, Renata POMAHAČOVÁ, Petra KONEČNÁ, David NEUMANN, jiří VOSÁHLO, jiří STRNADEL, Jindřich ČÍŽEK, Barbora OBERMANNOVÁ, Lenka PETRUŽELKOVÁ, Štěpánka PRŮHOVÁ, Markéta PAVLÍKOVÁ, Ondřej CINEK and Jana VYŽRÁLKOVÁ. Five years of improving diabetes control in Czech children after the establishment of the population-based childhood diabetes register ČENDA. Pediatric Diabetes. Spojené státy americké: Wiley, 2020, vol. 20, No 29, p. 1-11. ISSN 1399-5448. Available from: https://dx.doi.org/10.1111/pedi.12929.

@article{1591097,
   author = {Šumník, Zdeněk and Venháčová, Jitřenka and Škvor, Jaroslav and Pomahačová, Renata and Konečná, Petra and Neumann, David and Vosáhlo, jiří and Strnadel, jiří and Čížek, Jindřich and Obermannová, Barbora and Petruželková, Lenka and Průhová, Štěpánka and Pavlíková, Markéta and Cinek, Ondřej and Vyžrálková, Jana},
   article_location = {Spojené státy americké},
   article_number = {29},
   doi = {http://dx.doi.org/10.1111/pedi.12929},
   keywords = {diabetes; children},
   language = {eng},
   issn = {1399-5448},
   journal = {Pediatric Diabetes},
   note = {Bez afiliace k MU.},
   title = {Five years of improving diabetes control in Czech children after the establishment of the population-based childhood diabetes register ČENDA.},
   url = {http://dx.doi.org/10.1111/pedi.12929},
   volume = {20},
   year = {2020}
}

TY  - JOUR
ID  - 1591097
AU  - Šumník, Zdeněk - Venháčová, Jitřenka - Škvor, Jaroslav - Pomahačová, Renata - Konečná, Petra - Neumann, David - Vosáhlo, jiří - Strnadel, jiří - Čížek, Jindřich - Obermannová, Barbora - Petruželková, Lenka - Průhová, Štěpánka - Pavlíková, Markéta - Cinek, Ondřej - Vyžrálková, Jana
PY  - 2020
TI  - Five years of improving diabetes control in Czech children after the establishment of the population-based childhood diabetes register ČENDA.
JF  - Pediatric Diabetes
VL  - 20
IS  - 29
SP  - 1-11
EP  - 1-11
PB  - Wiley
SN  - 13995448
N1  - Bez afiliace k MU.
KW  - diabetes
KW  - children
UR  - http://dx.doi.org/10.1111/pedi.12929
L2  - http://dx.doi.org/10.1111/pedi.12929
N2  - OBJECTIVES: The Czech National Childhood Diabetes Register (ČENDA) is a web-based nationwide database that collects treatment and outcome data in children and adolescents with diabetes. Here, we present data from the first 5 years of ČENDA (2013-2017). METHODS: Data include characteristics of disease onset and annual summaries of key clinical care parameters from every patient treated by participating pediatric diabetes outpatient clinics. RESULTS: The database contains data of 4361 children (aged 0-19 years) from 52 centers (85% of all Czech pediatric patients). Of these, 94% had type 1 diabetes (T1D), 4.5% had genetically proven monogenic or secondary, and 1.5% had type 2 diabetes. In children with T1D, median glycated hemoglobin (HbA1c) decreased throughout the observed period from 66.3 to 61.0 mmol/mol (P < .0001, 95% confidence interval [CI] for change -5.6 to -4 mmol/mol). Consequently, the proportion of children reaching the target therapeutic goal of 58.5 mmol/mol increased from 28% in 2013 to 40% in 2017. The proportion of children treated with insulin pumps (CSII) remained stable over the observed period (25%). In a subanalysis of 1602 patients (long-standing T1D diagnosed before 2011), the main predictors associated with lower HbA1c were treatment with CSII, male sex and care provided at a large diabetes center (>100 patients). CONCLUSIONS: A significant continuous decrease in HbA1c was observed in Czech children over the past 5 years. As this improvement was not accompanied by appreciable changes in the mode of therapy, we assume that the establishment of our nationwide register has itself constituted a stimulus towards improvement in the care process.
ER  -

ŠUMNÍK, Zdeněk, Jitřenka VENHÁČOVÁ, Jaroslav ŠKVOR, Renata POMAHAČOVÁ, Petra KONEČNÁ, David NEUMANN, jiří VOSÁHLO, jiří STRNADEL, Jindřich ČÍŽEK, Barbora OBERMANNOVÁ, Lenka PETRUŽELKOVÁ, Štěpánka PRŮHOVÁ, Markéta PAVLÍKOVÁ, Ondřej CINEK and Jana VYŽRÁLKOVÁ. Five years of improving diabetes control in Czech children after the establishment of the population-based childhood diabetes register ČENDA. \textit{Pediatric Diabetes}. Spojené státy americké: Wiley, 2020, vol.~20, No~29, p.~1-11. ISSN~1399-5448. Available from: https://dx.doi.org/10.1111/pedi.12929.

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