REKTOROVÁ, Irena and Roberta BIUNDO. Non-invasive brain stimulation to treat cognitive symptoms of Parkinson's disease. PARKINSONISM & RELATED DISORDERS. OXFORD: ELSEVIER SCI LTD, 2019, vol. 66, SEP 2019, p. 1-2. ISSN 1353-8020. Available from: https://dx.doi.org/10.1016/j.parkreldis.2019.09.012.
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Basic information
Original name Non-invasive brain stimulation to treat cognitive symptoms of Parkinson's disease
Authors REKTOROVÁ, Irena (203 Czech Republic, guarantor, belonging to the institution) and Roberta BIUNDO (380 Italy).
Edition PARKINSONISM & RELATED DISORDERS, OXFORD, ELSEVIER SCI LTD, 2019, 1353-8020.
Other information
Original language English
Type of outcome Article in a journal (not reviewed)
Field of Study 30103 Neurosciences
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.926
RIV identification code RIV/00216224:14740/19:00108551
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1016/j.parkreldis.2019.09.012
UT WoS 000491684100001
Keywords in English TRANSCRANIAL MAGNETIC STIMULATION; NONMOTOR SYMPTOMS; MOTOR; IMPAIRMENT; SHAM
Tags rivok
Tags International impact
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 31/3/2020 11:09.
Abstract
Transcranial non-invasive brain stimulation (NIBS) techniques include particularly repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), although other noninvasive stimulation techniques have also been employed. The rTMS uses a rapidly changing magnetic field to induce currents and action potentials in underlying brain tissue. The tDCS involves the application of weak (1–2mA) electrical currents to modulate neuronal membrane potential. Although the precise mechanisms of NIBS aftereffects have not been fully elucidated, rTMS has been shown to modulate several neurotransmitter systems, increase neurotrophic factors, and induce changes on neuronal synapses by long-term potentiation (LTP) and long-term depression (LTD)-like mechanisms (for review, see Rektorova and Anderkova 2017). LTD-like mechanisms also apply for the underpinnings of tDCS. The aftereffects of NIBS depend on the stimulation protocols and on the precise coil/electrode placement as well as on the current “state” of the brain. Both rTMS and tDCS can be used to excite (high-frequency rTMS, anodal tDCS) or inhibit (low-frequency rTMS, cathodal tDCS) the underlying cortical tissue; the evidence pertains to NIBS applied over the motor cortex, but it may vary when the NIBS is targeted to sites other than motor cortices (e.g. L. Brabenec et al., 2015).
Links
NV16-31868A, research and development projectName: Ovlivnění kognitivních funkcí a konektivity mozku pomocí neinvazivní mozkové stimulace u pacientů s mírnou kognitivní poruchou u Alzheimerovy choroby
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