Function of chromatin structure and dynamics in DNA damage,
repair and misrepair: γ-rays andprotons in action

J 2014

Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action

JEŽKOVÁ, L, Martin FALK, I FALKOVÁ, M DAVÍDKOVÁ, A BAČÍKOVÁ et. al.

Basic information

Original name

Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action

Authors

JEŽKOVÁ, L, Martin FALK, I FALKOVÁ, M DAVÍDKOVÁ, A BAČÍKOVÁ, Lenka ŠTEFANČÍKOVÁ, J Michaelidesová A VACHELOVÁ, Emilie LUKÁŠOVÁ, A BOREYKO, E KRASAVIN and Stanislav KOZUBEK

Edition

Applied Radiation and Isotopes, Elsevier, 2014, 0969-8043

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.231

DOI

http://dx.doi.org/10.1016/j.apradiso.2013.01.022

Abstract

V originále

According to their physical characteristics, protons and ion beams promise a revolution in cancer radiotherapy. Curing protocols however reflect rather the empirical knowledge than experimental data on DNA repair. This especially holds for the spatio-temporal organization of repair processes in the context of higher-order chromatin structure-the problematics addressed in this work. The consequences for the mechanism of chromosomal translocations are compared for gamma rays and proton beams.

Links

GBP302/12/G157, research and development project

Name: Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii

Investor: Czech Science Foundation

Citovat

JEŽKOVÁ, L, Martin FALK, I FALKOVÁ, M DAVÍDKOVÁ, A BAČÍKOVÁ, Lenka ŠTEFANČÍKOVÁ, J Michaelidesová A VACHELOVÁ, Emilie LUKÁŠOVÁ, A BOREYKO, E KRASAVIN and Stanislav KOZUBEK. Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action. Applied Radiation and Isotopes. Elsevier, 2014, vol. 83, p. 128-136. ISSN 0969-8043. Available from: https://dx.doi.org/10.1016/j.apradiso.2013.01.022.

@article{1594218,
   author = {Ježková, L and Falk, Martin and Falková, I and Davídková, M and Bačíková, A and Štefančíková, Lenka and Vachelová, J Michaelidesová A and Lukášová, Emilie and Boreyko, A and Krasavin, E and Kozubek, Stanislav},
   doi = {http://dx.doi.org/10.1016/j.apradiso.2013.01.022},
   language = {eng},
   issn = {0969-8043},
   journal = {Applied Radiation and Isotopes},
   title = {Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action},
   volume = {83},
   year = {2014}
}

TY  - JOUR
ID  - 1594218
AU  - Ježková, L - Falk, Martin - Falková, I - Davídková, M - Bačíková, A - Štefančíková, Lenka - Vachelová, J Michaelidesová A - Lukášová, Emilie - Boreyko, A - Krasavin, E - Kozubek, Stanislav
PY  - 2014
TI  - Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action
JF  - Applied Radiation and Isotopes
VL  - 83
SP  - 128-136
EP  - 128-136
PB  - Elsevier
SN  - 09698043
N2  - According to their physical characteristics, protons and ion beams promise a revolution in cancer radiotherapy. Curing protocols however reflect rather the empirical knowledge than experimental data on DNA repair. This especially holds for the spatio-temporal organization of repair processes in the context of higher-order chromatin structure-the problematics addressed in this work. The consequences for the mechanism of chromosomal translocations are compared for gamma rays and proton beams.
ER  -

JEŽKOVÁ, L, Martin FALK, I FALKOVÁ, M DAVÍDKOVÁ, A BAČÍKOVÁ, Lenka ŠTEFANČÍKOVÁ, J Michaelidesová A VACHELOVÁ, Emilie LUKÁŠOVÁ, A BOREYKO, E KRASAVIN and Stanislav KOZUBEK. Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays andprotons in action. \textit{Applied Radiation and Isotopes}. Elsevier, 2014, vol.~83, p.~128-136. ISSN~0969-8043. Available from: https://dx.doi.org/10.1016/j.apradiso.2013.01.022.

Detailed Information on Publication Record